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From the Grave's hyperthyroidism to Hashimoto's thyroiditis (selenium, iodine)
 
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Published: 14 y
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From the Grave's hyperthyroidism to Hashimoto's thyroiditis (selenium, iodine)


I do not know if you read and pay attention to this

 

We've all heard that many doctors tell hypo patients, especially those with Hashimoto's thyroiditis, not to take iodine because it can aggravate their condition. The reason seems to be that selenium protects the thyroid gland from oxidative damage and this damage can increase significantly if iodine is supplemented. Taking iodine will increase thyroid hormone production and the production of H2O2 which damages the thyroidal cells. The lack of selenium prevents GPX from being able to protect the cells from this oxidative damage. While I doubt if most doctors realize why iodine should be restricted (it certainly seemed counter-intuitive to me at first), they have learned through experience that iodine can increase the thyroid damage in Hashimoto's. The information that selenium should be supplemented along with iodine is so new that most of them are unaware of it.

Here's what we have: Studies have shown that if iodine is low, selenium must also be kept low to prevent the hypothyroidism from becoming worse (from increased DI-I and T4 depletion, as explained above.) So if both minerals are low, then the person is hypo and gets a goiter, but the damage to the thyroid is kept to a minimum. More severe problems happen when either selenium or iodine is high and the other is low. If selenium is high and iodine low, then T4 to T3 to T2 conversion is accelerated without T4 being replenished, leading to a worsening of the hypoT. If iodine is high and selenium is low, then H2O2 is not degraded by GPX. Since H2O2 drives the thyroid hormone production, then the thyroid over-produces thyroid hormone (Grave's hyperthyroidism), the thyroid is damaged from the oxidation by the H2O2, and the end result is that the damaged thyroid ultimately decreases activity and hypothyroidism results (Hashimoto's thyroiditis). This could explain the observed progression of Grave's to Hashimoto's.
 

www.ithyroid.com/iodine.htm

Servus Mariusz

 

 

 
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