Praziquantel (Biltricide) kills adult flukes in the liver, GI tract, blood, pancreas, & lungs.
Albendazole (Albenza) is a systemic drug. It kills leftover fluke eggs, larva, & cysts & those scattered or disseminated throughout the body.
There are drug-resistant strains of Fasciola Hepatica (Sheep Liver Fluke), Fasciola Magna (Deer Liver Fluke), & Fasciola Gigantica overseas where Praziquantel has limited effectiveness (60% cure rate).
The drug Triclabendazole (Egaten) is used for those flukes in endemic countries (Egypt, N. Africa, Europe, SE Asia, etc.) (85% cure rate).
The veterinarian liquid suspension of Triclabendazole, Fasinex, is used overseas for livestock infected with drug-resistant strains. It's also used for humans when Triclabendazole or Egaten tabs are unavailable.
In trials & studies, other drugs had varying results but less effective cure rates: Nitazoxanide, Myrrh (Mirazid), Clorsulon, Bithionol, & Artesunate.
Fasciola hepatica (Sheep Liver Fluke) (left)
& Fasciola magna (Deer Liver Fluke) (right)
A-Fasciola Gigantica & B-Fasciola Hepatica
Triclabendazole (Egaten & Fasinex) are banned for sale & shipment to the US & Canada. They can be obtained through bootleg sources, but the cost is very expensive.
For rare cases of these flukes in the US, a doctor can request Triclabendazole (Egaten) on a special-needs basis from Novartis or Bithionol (Lorothidol or Bitin) from the CDC.
Before obtaining Tricla/Egaten/Fasinex for self-treatment, suggest lab testing to confirm infection w/these flukes. This step might save you a lot of money in the long run!