How much Grapefruit-Seed-Extract would need to consume to reach 1g of benzethonium chloride, a potentially fatal dose? Well, 10 drops of a popular product is claimed to contain 100mg of GSE, and one tablet of another contains 125g GSE. If such Grapefruit-Seed-Extract products contain 8% benzethonium chloride by weight, then 1250 drops or 100 tablets might be a fatal dose of GSE.
On a more positive note, "Benzethonium chloride showed no evidence of carcinogenic activity in 2-year skin studies on male and female rats."
This report by ScienceLab.com about the toxicity of benzethonium chloride is quite alarming: "The substance is toxic to mucous membranes. Repeated or prolonged exposure to the substance can produce target organs damage. http://www.sciencelab.com/xMSDS-Benzethonium_chloride-9923044