Nystatin is an antifungal medicine used to treat infections. It is not absorbed in the bloodstream, and is instead only applied to the surface of an infection. It can be taken several ways: through a tablet, lozenge, or liquid held in the mouth until dissolved; a tablet or cream for use on the vagina; and as a powder or cream for use on skin.
Interaction with Fungi
Nystatin is effective in preventing infection of Candida fungi, which is the fungi most often found in the mouth or throat. In order to prevent fungal or yeast infection, the nystatin binds itself to the ergosterol found in the fungal or yeast membrane and begins dissolving the membrane. With the membrane gone, the fungal or yeast cell begins losing vital constituents, and dies.
Nystatin may have some negative side effects, including mouth irritation, diarrhea, nausea or vomiting. On the skin, a rash or itching may develop. Severe side effects, like inflammation or trouble breathing, should be addressed with a doctor. If pregnant or planning to become pregnant, do not use nystatin.