It would be very helpful if you had a naturopathic physician to thoroughly evaluate your situation and provide guidance. Not knowing your full health history, we can only discuss generalities.
You would probably be surprised how many people there are who take enemas every day, many of whom have been doing so for many years and are in excellent health today. That having been said however, it is essential while taking frequent enemas that you maintain your bodys electrolyte balance and replenish the "good" bacteria in your large intestine.
A teaspoon of Sea Salt or non-iodized table salt added to each pint of enema solution will help maintain electrolyte balance, as will a diet rich in sources of Potassium, such as bananas, unsugared citrus juices, and Welches Concord grape juice. Acidophilus in supplement form, or added to dairy products can also assist in maintaining healthy microflora in your digestive system.