I remember trying CardioRenew a few years back but I didn't finish the program. AFter about 2 or 3 days into it I felt a sharp pain in the left side of the heart area. Maybe it was loosening up some plaque. I'm wondering if I should try again. I ended up letting the product expire and I threw it out because I wasn't ready to give up my greasy junk food then and kept putting it off.