Might depend on how old you are, what your diet has been for carbohydrates in the past, how much of any kind of drugs or OTC's you have taken, what you can get away with when you do a bowel cleanse. The bowel cleanse means getting the old, sticky junk softened up on the colon walls and flushing that nasty, usually black, rope-like stuff out of there. The Schulze #1 formula gets the muscles to working properly (that means good peristalsis)and the #2 formula pulls it off the colon walls.