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Trazadone Is An ANTIADRENERGIC Agent.


From Wikipedia, the free encyclopedia

  (Redirected from Antiadrenergic)

sympatholytic drug is a medication which inhibits the postganglionic functioning of the sympathetic nervous system (SNS).[1] Though some are indicated for various functions, they can all be used as antihypertensives.




Antiadrenergic agents inhibit the signals of epinephrine and norepinephrine. They are primarily adrenergic antagonists, inhibiting adrenergic receptors, but there are exceptions: clonidine is an adrenergic agonist on the α2 receptor, since this receptor is located presynaptically to inhibit further release of adrenaline and noradrenaline.

Other ways of inhibiting adrenergic signaling is by catecholamine synthesis blocking, e.g. by methyltyrosineReserpine works by inhibiting transport intosynaptic vesicles of noradrenaline by inhibiting the VMAT transporter.

[edit]In hypertension

Many antiadrenergic agents used as antihypertensives include:


[edit]External links



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