The violent reaction to humaworm may have been a die off reaction. I encourage you to keep taking it, split a capsule in half and take one in the morning and one in the afternoon to see if that will slow up the detox symptoms. You are right on spot to take a systemic approach. I had a bad case of really mean face mites that took two months to clear up. I rotated between xmfl, zz, floucinonide and a concoction of anti-parasitical essential oils mixed with orange tko. It finally went away and now I'm protecting my skin by washing it twice daily with cold cream. The demodex solutions products are very good and they work well, but rather expensive.