In 1936, in the Journal of Physiology, C. H. Best and J. Campbell described a substance from the pituitary gland which had the specific capacity of accelerating the mobilisation of depot fat. They called it adipokinin. In 1948, two Americans, Rudolf Weil and deWitt Stetten, Jun., wrote in the December number of the Journal of Biological Chemistry:
"During fasting, under conditions in which an increase in the mobilisation of depot fat might be anticipated, there appears in the urine a material capable of provoking such an increase, which at least superficially resembles pituitary adipokinin."
In 1954, in the Canadian Journal of Physiology and Biochemistry, Collip described the isolation of a metabolism-increasing factor from the pituitary.
What all this amounts to, in untechnical language, is this: if you take a fat rabbit and inject it with a sub- stance obtained from the urine of a fasting rabbit, the fat rabbit will get thinner. Research into the nature and effects of this fat-mobilising substance in fasting urine is going on at the present time. Work with human volunteers is giving encouraging results similar to those in rabbits.
The urine of fasting humans contains large quantities of a material which when administered to mice will increase their utilisation of stored fat.
So this means, urine-fast promotes rapid weight loss for obese people, even faster than with water-fast!
Urine therapy, without fasting, also promotes weight loss since this fat-mobilising substance is produced almost all the time. Overweight people produce it in larger quantities than slim people, so effect is greater where its needed.