I read his colon even weighed more from impacted fecal matter. The interesting thing is that some people have disputed that this is true based on the fact that John Wayne did not have an autopsy performed because they knew he was terminal. So how did they know about the health of his colon? John Wayne donated his body to Science and it was the team of doctor/scientists that disected his body that observed the health of his colon. This is based on my research, however I was not there and can't say for sure. It is known that the average human carries between 5 and 25 pounds of impacted fecal matter in their colon. So it is very concievable that The Duke could have been carrying more.