You'll know when you're done, nobody can answer that Q for you. As you go on you'll see that the detox comes in waves. And, when you feel that you may be "done", you can always get a loading test. Info on that at http://www.breastcancerchoices.org
And, how much to take? Once again that's up to you....No doubt that detox happens at 50 mg, or lower, doses. I remain unconvinced that MORE detox happens at higher doses as a rule of thumb. There has to be a point of diminishing returns...
Guy Abraham, MD....on detoxifying the body of unwanted halides. The dosage that he's refering to here is 37.5 mg per day.
"Is there a practical and simple way to lower the body's burden of fluoride and bromide? It has been known for sometime now that bromide competes with chloride in the extracellular space and that the total molar concentration of bromide plus chloride remains constant. (8) This concept has been used to decrease extracellular bromide levels by saline loading. However, the presence of bromide in the thyroid gland (9) and the central nervous system (10) suggests that there is another intracellular "pool" of bromide, not responding to chloride. In the thyroid gland, bromide competes with Iodide for uptake, oxydation and organification.
"Therefore, increasing Iodide intake should lower bromide levels in the thyroid, preventing and reversing its thyrotoxic and goitrogenic effects. The same applies to fluoride. Galletti and Joyet (12) evaluated the effect of 5-10 mg fluoride on thyroid functions in hyperthyroid patients. Although fluoride inhibited the iodide-concentrating mechanism of the thyroid, fluoride did not accumulate in the thyroid. Based on their radioactive tracer studies, they concluded "Fluorine does not impair the capacity of the gland to synthesize thyroid hormones when there is an abundance of Iodide in the blood." Therefore, fluoride toxicity depends on iodide supply."
"Following supplementation with the iodine/iodide preparation, there was a progressive increase in the excretion of fluoride and bromide. With 3 tablets, the 24h excretion of fluoride was 17.5 times baseline level; and for bromide, 18 times baseline level. These high levels persisted even after one month of supplementation at 3 tablets/day, being 15 times baseline level for fluoride, and 16 times for bromide. After one month, the estimated total amount of halide excreted was 24 mg fluoride and 8700mg bromide. It is unlikely that such large amounts of halides came from the thyroid gland. It would seem that the whole body is being detoxified. Orthoiodosupplementation could be used under medical supervision to detoxify the body from unwanted halides in a manner similar to the use of EDTA for the detoxification of heavy metals."
"As can be seen from Table 1, little Iodine was secreted at baseline. The data indicates that all of these patients were Iodine deficient at baseline. After ingesting 50mg/day of an iodide/iodine supplement (Iodoral®), repeat testing was done on day 1 and after 30 days of supplementation. As Iodine was supplemented, as expected, the excretion of iodine increased—from 40.2% to 66.15%. Increasing the iodine load also increased the excretion of the toxic halides bromide and fluoride.
This study showed that the body was adapting to the iodine load and becoming saturated with iodine while at the same time detoxifying from the toxic halides bromide and fluoride. This study provided me with the answer to the two questions previously posed. Because of the elevated levels of toxic halides in the environment and in the food supply, iodine levels have not only fallen but larger amounts of iodine are necessary to correct iodine deficiency as well as to promote a detoxifying effect of heavy metals.
This study showed that the body was adapting to the iodine load and becoming saturated with iodine while at the same time detoxifying from the toxic halides bromide and fluoride. This study provided me with the answer to the two questions previously posed. Because of the elevated levels of toxic halides in the environment and in the food supply, iodine levels have not only fallen but larger amounts of iodine are necessary to correct iodine deficiency as well as to promote a detoxifying effect of heavy metals."