Well, I tried Lugol's directly on my mole and became a laughing stalk at work and home. It looked just like that foot pic. I do agree we are all different, however, palm skin and bottom part of your foot skin are different compared to other skin. I have also applied it my palm without any problems, but any other areas of my body is a huge problem, my skin just burns instantly. IMO one should try out areas that are covered up by clothing and then try other areas that are exposed. My burnt stains on my face are still there.