Of course everyone is different and so we will have different reactions. On day eight at 16 drops I brought it all up. The next day I went back to 12 drops and for the next few days I improved till day 12 and 13 when I thought I'd died and gone to heaven. I had energy like I couldn't believe...............then I collapsed, energy wise for three weeks. Today I noticed better brain function, and more energy. If you can possibly hang in there I think you will benefit.