i've had really bad constipation that hasn't been very responsive to anything for the past 3 years. your constipation sounds like mine. i had problem doing a Liver Flush because i ended up retaining some of the stuff the laxatives should have flushed out. it's been horrible. do you take your thyroid meds sublingually or do you swallow it? i just got my blood taken earlier in the week for thyroid, candida and some sex hormones. best of luck to you on your road to health.