Hello hilli, I was diagnosed with clinical depression in 1995. I was put on three different anti-depressants before I came to my senses and realized those medications were stealing my soul and turning me into a zombie (yet I thought I was finally "normal" when the medications first kicked in). Since being prescription free I have done a lot of cleansing including liver flushing, colon cleansing, parasite cleansing and several Master Cleanses, juice and water fasts. In each of these various cleanses I have had to deal with bouts of depression. Some of these feelings may be circumstantial, but I have come to believe that as we cleanse we release toxins and perhaps even the bio-chemical residue of toxic emotions. Try and stay aware of this fact. Keep a journal of your feelings during cleanses, your dreams and memories that arise. I have had to deal with a lot of bad stuff during these episodes. I even had to relive some terrible instances of abuse I had pushed back in memory, but were still affecting my thought patterns and behavior. Cleansing and detoxing is very difficult for many of us. If you can push through the feelings of being overwhelmed, hopelessness, and sadness and anger then you can see the benefits of an emotional detox as well as a physical one. It is very hard, but when you come out on the other side, it is worth both the emotional pain and the physical discomfort. You can cleanse your emotions rather than mask them with drugs and that is great healing for some of us.