What we do know so far is that if a person takes too much and gets really sick they will not want to do Miracle-Mineral-Supplement anymore.
If I had to recommend to a DF Miracle-Mineral-Supplement , I would insist she/he stay under the nausea "sick" point unless she was incurable or had the time to give MMS 100% of his attention.
I am using Humbles advice on my teen DD. He suggests staying one drop under nausea. However, DD did not experience the nausea. She did experience loss of appetite. So I am striving to keep her one drop under loss of appetite.
The good news is recovery seems to be fairly swift once MMS is no longer active and I eat something and then cometh the runs.
Unless your body is adamant about detoxing through a cold. My DD got hit immediately with the detox cold after giving her 8 drops.
Presently, I have her on 2 drops 2X a day. In the middle of day she drinks Vitamin C, and gets her Potassium, Mag, Zinc.
I intend to get her and I to the 4 to 6 drops 2X a day and hold it there. That is what humble refers to as the maintenance dose.