My daughter has PCOS. Please take a look at the curezone Iodine forum. She started taking Iodine in July (Lugol's solution)-- 50 milligrams a day. By October, her menstrual cycle resumed. She had not had a cycle in a year--and before that she was quite irregular. She'd been to a naturopathic doctor, ate a very healthy diet, but it seemed she was lacking iodine--and that has made a tremendous difference.