According to Dr Saul Pressman,with vaginal insufflation 80% of the ozone goes to the lymph and 20% to the blood. If so that's good. The lymph is where most of the toxins are stored. Also according to Dr Pressman, when doing rectal insufflation, most of the ozone gets absorbed into the blood. I would suppose that would depend on the ability of the colon to absorb anything.