Yes, mercury causes anxiety and fatigue, a horrible combination. I had days where I was so exhausted I didn't want to live and other days where I was wired like I was on caffeine. Even when exhausted I was unable to get to sleep, often it took 24 hours or more for me to get tired enough to sleep. One thing for those who get the mercury out, refrain from caffeine because it hampers the ability of mercury to leave the body. I quit for 4 months while I was chelating.