Well, I saw the surgeon - one who has a very high reputation. He said my cataracts were Grade 4, nuclear + PSC mixed, and the lens hardness was +4 on a scale of 0 to 6. He said that if I asked him to remove my cataracts, he would do it, but frankly admitted to me that "cataract surgery does not restore normal vision to what it was before the cataracts", and that patients experience all kinds of trouble post-op, so I should prepare myself for that eventuality. Of course, when you're faced with going blind, you don't have much choice, and many people do have good visual outcomes.
He also said I knew far more about cataracts than he did, although his wife was also an ophthalmologist and a lecturer on the retina and cornea at a university. I asked him to introduce someone doing cataract research, and he echoed my lament that he knew of no-one in this country. Finally, I said I would try to hold out until maybe December, when there may be clinical trials of non-surgical methods.
It's been a while since I posted here. Recently, I slipped on a smooth rock surface, landed flat on my back and fractured 3 ribs, as well as compressing the right lung. Which has meant that I'm unable to lie flat, or sleep in a bed any more. I'm hoping that within a month or two, the ribs, cartilage and tendons will have healed sufficiently to allow me to sleep in a bed again. Right now I have to sleep sitting in a chair, sprawled forwards on a table and I can tell you, it's not much fun. It also means I cannot lie down to have cataract surgery either.
The hospital focused their treatment on the lung, more or less ignoring the ribs, so I went to a chiropractor who taped and strapped the ribs with elastic material in an effort to hold them in alignment while they heal. He also applied a microwave heating device to the ribs, and the feet which are swollen due to my sleeping position. But the microwaves seem to have made my cataracts a whole lot worse, which is not surprising since I have irradiation cataracts. I'm going to refuse future microwave treatments. Not to mention the 10 chest X-rays, and the CT-scans I had - they also made things yellower and foggier. If a light is shining in front of me, I can barely see my hand in front of my face. If I darken the room, I can see better although it's still yellow.
Which brings me to my main point. Most of us have radiation cataracts, meaning that ionizing radiation, microwaves or UV are the root cause of the damage to our eye lens. Therefore, we need ways to halt the damage, and reverse it if possible. A few years ago, Trevithick et al had found that a combination of pycnogenol, beta-carotene and vitamin C partially reversed irradiation cataracts. So I now take pycnogenol, alpha-lipoic acid, vitamin E and vitamin C for this purpose. I just hope that one day, I will notice an improvement.
THREE-STEP PLAN TO REVERSE NUCLEAR CATARACT WITH EYEDROPS
(1) EV06 eyedrops to break lens disulfide bonds and soften the lens.
This would allow (2) and (3) below to penetrate the lens.
Contain lipoic acid choline ester.
Bought by Novartis Pharma (which also has a huge surgical lens business) as an eyedrop to cure presbyopia for $465 million. Has already passed Phase II clinical trials in the US, but Novartis says it hasn't. Novartis has no plans to release this eyedrop which is therefore unavailable.
(2) AGE-crystallin crosslink breaker. Would contain phenacyl thiazolium bromide (PTB, synthetic) or chebula (Ayurveda, natural), or any other crosslink breaker. PTB was shown, at the University of Arkansas in 2008, to break crosslinks of AGEs with alpha-crystallin, and thereby reverse loss of chaperone function of alpha-crystallin. This discovery is the key to curing cataract blindness in 90 million people worldwide and alone is worth a Nobel Prize. The eye profession has no plans to use this discovery, therefore no intention to cure world blindness, and it is therefore unavailable.
(3) Alpha-crystallin stabilizers (sterols)
This means lanosterol and other sterols. They have the ability to refold and stabilize alpha-crystallin liberated by (2) from its shackles to AGEs. Once stabilized, alpha-crystallin will then interfere with the electrostatic attraction between beta- and gamma- crystallin protein molecules by masking the electrical charges on their surfaces, thereby separating the molecules, and breaking up large molecular aggregates into smaller ones. This will restore optical transparency to the lens, curing the cataract.
Lanosterol eyedrops are available, but cannot work on alpha-crystallin until the lens is firstly softened, and the alpha-crystallin is secondly released from its bonds to AGEs (Steps (1) and (2)) above.
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