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Trimethylaminuria (TMAU) Support Forum
Forum Description
Last Message  5 months ago

Trimethylaminuria [TMAU/tmau] is a metabolic condition involving hepatic dysfunction in the flavin monooxygenase (FMO3) system (impaired N-oxidation of TMA) wherein individuals excrete a fishy body odor in urine, sweat, breath, and other body excretions.

Although it was first described in 1970, only 30 cases have been reported in the world's literature and the phenotype is still not well described. Affected individuals can be symptomatic in infancy or later on in childhood or at puberty, and there appears to be marked variability and/ or expressivity between populations. Some patients don't become symptomatic until adulthood.

BROMHIDROSIS, Trimethylaminuria, TMAU

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