- There are two distinct functions of Selenium- One is as an antioxidant or detoxifier (Heavy Metals) and as a building block of proteins and enzymes. This form is stored in the format of Selenite and Selenomethionine by the tissue.
- The other requires further conversion, first to Selenomethionine then to methylselenol then further into anti-cancer anti cell differentiating functions.
NOTE: By fighting cancer at this level it uses apoptosis to rid the body of the faulty cells in a carefully-orchestrated process instead of necrosis which could cause massive toxicity and actually end up spreading tumors.
Table 3 on page 6 is also worth looking at; I interpret this as supplementing with Selenium from yeast (a combo of Elemental and Selenomethionine) is best only to be beaten out by the Brazil nut and SeMC.Since the intake of iodine seems to trigger huge reactions by the immune system to rid itself of cancers the intake of SeMC should be considered. Another consideration should be the availability of the pathways to do all this converting. I have now seen three with low methionine levels and high Homocysteine levels which leads me to believe their body is incapable of the conversion process without affecting the Methylation Cycle which may trigger depression/fatigue and kidney trouble.
Conclusion: SeMC appears to be a great addition for those with a less than ideal Methylation Cycle, but in this form we don’t get the antioxidant, detoxifier, protein building and enzyme function and still require a second source as in Brazil Nuts or Selenium from Yeast.More on Methylation Cycle: http://aor.ca/int/related_research/same_400.php