Johny Apple Bomb
It depends on. How well your body removes die off. Type of machine your using. How healthy your kidneys and liver are. What type of condition your trying to treat.
I use to use my machines every day for at least 30 minutes. MY only side effects were fatigue with my EMEM. When I used a pad Zapper device set at Herpe's Zoster frequency I had a mild outbreak.
Just drink a glass of clean water - distilled water before and after. Better yet ozonated, chilled distilled water. If you feel bad you know you should probably cut back.