Hello - Let's take these one at a time:

1. You can take them 8-12 hours apart - you just want the herbs to be in your system 24 hours per day for 30 days. The herbs are so potent that many people experience heartburn after taking them - eating will relieve this heartburn. That's why we recommend eating 30 minutes after taking them - of course, you don't have to eat after them, but it will help the heartburn feeling.

2. HUMAWORM treats the entire body at the same time - including the head area.

3. You may be experiencing die-off symptoms right now. You body is waging war against the parasites and toxins and the symptoms that you had before cleansing might get bad for a day or so during the cleanse. It is actually a good sign. Make sure that your bowels are working properly and that you are keeping your body hydrated - this helps lessen die-off. After the 30 day cleanse is over you can eat 1/4 teaspoon daily of: onions, garlic, sage, thyme, ginger, cloves and cinnamon. These are anti-parasitic in nature, but they will not cause super parasites. You can then do another cleanse in 90 days.