Too much fasting, not fasting.
You don't need much science, it is common sense. I firmly believe that there is a line where destruction of the body begins- if you fast too much with the final consequence being death. And when destruction begins, one of the first organs that starts to fail is adrenal glands. Among many things they produce sex hormones and very important- mineralcorticoids. Too much fasting just shuts down operation of these important hormones. All hormone system goes amok. In the end too much fasting is a terrible stress to body. Once again, I am talking not about fasting, but about too much fasting. When you experience all that on your body you don't need AMA or pubmed to tell is true or not.