It helps to take it orally but that will mostly help the circulatory system, stomach and small intestine. Using it in an enema applies the benefits directly to the mucosa lining there.
I felt a noticeable relief from brain fog and other allergic reactions. It made it easier for me to do multiple enemas without ever feeling the burning pain, irritation other people have mentioned experiencing.
Basically, it is a gentler form of Colosan or H202, so any benefits you hear of thanks to those methods apply here. It oxygenates the colon, but slowly and gently. :)