The ingredients are the following:
BIONECT® Cream - Hyaluronic acid sodium salt (Hyalastine®),
polyethyleneglycol 400 monostearate, decyl ester of oleic acid, emulsifying wax, glycerol, sorbitol solution 70%, sodium dehydroacetate, methylparaben, propylparaben, fragrance, purified
BIONECT® Gel - Hyaluronic acid sodium salt, sorbitol solution
70%, sodium dehydroacetate, methylparaben, propylparaben,
carbomer 980, sodium hydroxide, purified water.
My question is what is the difference between "hyaluronic acid sodium salt" and "sodium hyaluronate." I think they are the same. Jsl123 posted a few months ago information from Wellness Resources, who claim sodium hyaluronate should be avoided (take their criticism with a grain of sodium salt, though):
"Avoid the form of hyaluronic acid called sodium hyaluronate (check the label). This is a cheap, synthetic HA that is NOT the naturally occurring compound made by all cells of your body. It has salt attached to every single disaccharide unit. Not only does this increase sodium intake, the HA molecule itself is abnormal."
Many sites trumpet their low-molecular weight (measured in daltons) hyaluronic acid as being able to penetrate to deeper layers of the skin, and some sites say that high-molecular weight Hyaluronic acid does not penetrate the skin at all. As far as Bionect goes, on its patent request the molecular weight of Hyalastine® is cited as 50,000 to 100,000 daltons. Some brands boast 3,000-8,000 daltons of average molecular weight.
According to this journal article
, low molecular weight hyaluronic acid does have an immune system stimulating effect and may be useful in fighting Candida albicans and gram-negative bacteria (such as h. pylori) and is bacteriostatic towards gram-positive bacteria (such as steptococcus and staphylococcus aureus).
The hyaluronic acid I used was organic, claimed to be on the low end of molecular weight, and the ingredients were: Purified Water, Hyaluronic Acid (1% solution-100% pure), Leucidal (natural preservative derived from radishes). Most hyaluronic acid sites will say to use it for two weeks to see any effects. I found greater effect while combining it with emu oil, as I stated in a previous post.