I have been having some doubts lately about whether the Cutler protocol can be considered safe to try. I have read a lot of the success stories but it's hard to tell just how many there actually are. I realize many of the regular members here believe the protocol has worked for them. I wonder if they could be a minority compared to the overall number of people who attempt the protocol. Couldn't some people that have positive effects just be responding to other supplements?
Have many parents had success with chelating their autistic children? I have never heard definitive results about this.
That said, I'm sure it is normal to have doubts but I really don't want to make my situation worse. I recently read this doctor's opinion ( http://www.drbuttar.com/blog/?p=96
) that DMSA is a neurotoxin. I also read a response from Cutler where he indicates it is not a neurotoxin and that it would compromise the immune system before the brain. Are there studies that show this? Should I be worried about a compromised immune system as well? Neither Cutler nor this doctor seem to have great evidence either way. I understand Cutler's approach is to present this information in layman's terms but it can sometimes feel unprofessional.
With all of the talk about the dangers of using ALA inappropriately, I thought surely there would be negative reviews of the product in online stores. I don't see any negative reviews out of hundreds on the iherb reviews of the various brands. Once again, this isn't any kind of proof, but adds to my doubts (not that I am about to take ALA outside the protocol).
I understand that there is bound to be conflicting information. I don't mean to make any claims one way or another, just to say it is difficult not to be a little overwhelmed by the vast amount of unknown variables. I am currently going through a several week period of brain fog after my first round of DMSA and wondering if I made the wrong move. It is quite upsetting because before the round there were times when I felt quite good, now that is much more rare. I guess I'm torn on what I should do next.
I'm assuming you don't have silver fillings. Is that correct?
I've been chelating for a few years, including the use of the Cutler Protocol. I can tell you that, all-in-all, I'm feeling much better.
Chelating will make you feel worse before it makes you feel better, and everybody reacts differently to each chelator. I wouldn't necessarily worry if you are feeling worse after using DMSA. It depends on how much worse you feel. You could try a different chelator if your reaction is too bad.
It took me 6 months of chelating before I obviously felt better. I generally took only a chelator plus a multivitamin.
A trip to a sauna and drinking a lot of water may help you feel better if you haven't tried them.
Now, you say 6 months, and I'm approaching the beginning of month 6. I've slowly moved up to 40mg of ALA, and am considering taking 50mg next time I use it.
I've heard some people say that around 6 months in, the body suddenly starts dumping mercury much faster. Is that true? While I met with increased energy (to the point where I frequently have the desire to go for a walk, and I walk multiple times a day), and some mild weight loss... that's about it. Not even improved mood that I can tell, and I recently added magnesium citrate and a B complex to my routine.
So, what was your experience like, as well as other experiences you've read, and when can I expect major improvements?
You are really lucky to be tolerating 40 mg ALA after 6 months! After two years I've still never been above 12mg ALA and 25mg DMSA, yet have gotten really nice gains. I could almost certainly tolerate higher doses but I want to get on with my life. I'm not as productive when on round with max doses of LA.
Early gains in energy are common. However many report some worsening of symptoms in the roughly 6-9 mo period. I would not expect that to be so bad for you since you are using such high doses of LA.
Mg is one of the essential supplements while using Cutler's system. Bs are in the next group of valuable supplements.
I'd be really grateful for an update from you in a couple of months. I won't be surprised if you have a really mild "dump" period.
I started 50mg this current round (I'd been on 40mg long enough that I felt it was time to move up, as the side effects were going away and I didn't think I was making much progress anymore).
Anyway, symptoms get worse around months 6-9? That's the time of the big "mercury dump", right? What can prevent this? I see little improvement, but the side effects of taking ALA (including mild brain fog at times, when on round) indicate to me that SOMETHING is happening.
I agree that the Cutler protocol may not be a successful protocol for everyone. I spoke with someone at DAN and he said that the Cutler protocol is about 9 years old and considered outdated. There are other protocols that are safer (e.g. OSR). I stopped using the Cutler protocol a couple of months ago and began using DHLA Nano Plex and have had remarkable results. I use it in addition to taking the following Liver Cleansing herbs (Liver Life and Liver Complete) for three to four weeks.
== Remember what I previously wrote to you. It is not just what you take but how you take it--the protocol. Dosing: how frequently, how much, rounds, supporting supplements, etc. Beware of those who will tell you to take things randomly. You don't want the mobilized (kicked up) heavy metals bouncing around randomly!
== There is a lot to like about Boyd Haley, the one who is behind OSR for human consumption. (I previously gave you links to several of his videos) However OSR is a yet to be proven new medicine. There are some encouraging reports but also difficulties too--I think certain liver issues in some. This might just be something that certain people should not take or something that is not going to be well tolerated by many. It will need further testing. OSR is not available in North America.
Re liver "cleansing herbs".
== Be careful if you have liver problems due to Hg. You don't want to put added stress on the liver. There are more conservative options.
Most of the links in that post appear to be dead. I don't think it is still available
Interesting writeup on the chemical in Wikipedia. It definitely does seem to chelate mercury, however allegedly it only does it under extremely acidic or extremely alkaline conditions, so I'm not sure how it's going to perform in the human body?
Like most thiols, BDTH2 binds to mercury salts to form thiolate complexes. In principle, it could be used to remove mercury from water for industrial applications under a wide range of conditions, including the high pH and cyanide of the effluent from gold mining. In industrial use, BDTH2 is easy to make, does not form disulfides, and can be used either as-is or in the form of sodium or potassium salts that are more soluble in water.
BDTH2 binds to mercury with a strong, nonpolar covalent bond within a water-insoluble organic framework. The resulting BDT–Hg precipitate is stable, and leaches mercury only under highly acidic or basic conditions. BDTH2 also binds to other elements, including arsenic, cadmium, copper, lead, and selenium. It is effective and economical for removing small traces of mercury from polluted soil, as the precipitate is inert and can be left in the soil after treatment.
Dietary supplement and controversy
Despite the fact that chelation therapy has not been shown to have a beneficial effect, BDTH2 had been marketed under the name OSR#1 as a dietary supplement for treatment of autism. The U.S. Food and Drug Administration determined that BDTH2 is a drug rather than a supplement and issued a warning, resulting in its removal from the market. The main proponent of the compound, Dr. Boyd Haley, was chairman of the department of chemistry where research is also conducted on the utility of this compound for remediation of heavy metal pollution.
Regarding heavy metal chelation, so far I only know there are several options:
1. Cutler protocol, using DMSA & ALA
2. DMPS, with DMSA/EDTA etc. (it really depends which heavy metal you have in your body)
3. Chlorella & Cilantro
So far I know there are people who recovered from each of options above. So far the conclusion I can draw is that it's all depend on your condition. What is important is that you can work with knowledgeable doctor who can access your whole condition properly and be able to do the right chelation protocol for you. The 3 options I mentioned above has its own pluses and minuses, and the good thing is to find right doctor who can diagnose properly for you (and not grossly applying the only method he knows for you, regardless of your condition.)The problem with chelation if you are not looking thoroughly, you might as well turn the toxin around in your body and thus makes the condition worsen. Honestly, if I can't find the right doctor who I am comfortable to work with, I will not embark on any chelation protocol by my own.
yes some people respond very very poorly to it. i personally dont like it based on people who seem to be on it for years and not improving (yahoo groups) clay baths+cliantro on foot pads is a natural alternative. (ive seen pre post doctors data hair tests for these yes it works)
I have been here for some time, reading and following discussions and comments.
Firstly I want to back ERM's post. This particular comment is where I am: """Honestly, if I can't find the right doctor who I am comfortable to work with, I will not embark on any chelation protocol by my own."""
I found an excellent doctor - with both personal chelation experience and good consultative contacts to tailor my chelation protocol. Without going into lots of detail there are a number of analytical processes wisely used both starting and during chelation.
In reading many posts here over some time two things stand out.
Although I read some discussion about initial analysis there is little discussion of its ongoing role in chelation. There is some mention of supports that is not really discussed or well developed.
To sum up my treatment without going into details.
There were three sets of blood tests 23 in total. On going monthly reviews principally following liver kidney and various micro-nutrients. IV DMPS 24 hr urine. Hair analysis.
Genetic typing/saliva analysis.
I am chelating with four different agents and use nine different nutritional supports. As well as those nutritional supports there are six dietry supplements to assist/ensure HM removal.
So far all well at four weeks continuous treatment. First set of blood tests are fine.
I have respect for all parties here and do not want an argument about this or that protocol.
In summary of both my reading and current program: People's responses to HM's and their treatment protocols are individual. There is the information about to sort out individual protocols. Finding a well informed doctor could be the answer. That appears to have be the case for me.
"In summary of both my reading and current program: People's responses to HM's and their treatment protocols are individual. "
Yes, but only to some extent. We are all mammals. We'd be wise to account for the effects that chelators have in mammals while also being alert for the additional variations in effects.
Re IV Chelation. Think carefully about it. With IV you get a relatively big infusion of chelators for a relatively short time (relative to low, frequent dose (cutler) protocol for a long weekend or longer). I liken it to dusting your dining room table with a leaf blower. Yes it will remove dust, but you can bet it will leave more dust on your chandelier which is more difficult to clean. You won't notice much difference if the table isn't very dusty but if there is much dust, it will be obvious.
dmps backfire.com is probably the worst chelating related website on the Internet
They've got stories on there from people who had IV DMPS who still had mercury in their mouth! Of course they're going to have a bad time! What kind of moro_n injects mercury chelator into the veins of somebody with Mercury fillings still in their mouth?
Cutler says he knows of some of those cases at dmpsbackfire.com and many more like them.
I hear you about chelating while Amalgam is still present, but it has been done and many more are doing it with cilantro and ALA in supplements without knowing it. The ones who actually have and Hg problem are getting hurt by it.
A close friend is one. She lost 6 months of nice gains from Amalgam removal and frequent dose chelaton in a week of inappropriate ALA use (mfgr added it to new version of her multi vitamin).
you may be entirely correct, however I'm just saying you simply can't draw any conclusions regarding DMPS or IV chelation based on cases of people injecting a chelator into their body while they have a whole mouth full of mercury
I'm saying the website is useless. IV chelation may be a really bad idea, but not because of anything that appears on that very very poorly documented website
Newbies don't often realize how dangerous it can be to randomly kickup heavy metals, especially mercury. That site is quite useful at making the point that they should be very careful about what they do or what they allow a doctor to do to them.
Chelation for long term, low level exposure is still in its infancy. The doctors are learning on the fly. Be careful about letting them use you as a lab rat.
I don't consider the Cutler protocol safe. In fact, I think it might be dangerous for some people. The problem with chelation is that whereas a certain protocol can work for some people, it can be very dangerous to others. I tried it, but it didn't seem to work for me.
DMSA is NOT safe. It can be quite dangerous, especially in larger dosages. Any harmful and detrimental effects will probably show in the long run. Again, it depends on the individual.
I chose to use natural and safer products to chelate the huge amounts of lead in my body: water and dry fasts, Green Clay taken orally, clay baths, apple pectin, kefir and colonic irrigations, humifulvate, milk thistle, lecithin, omega-3, megadoses of Vitamin C and lots of chlorophyll rich greens.
"...The problem with chelation is that whereas a certain protocol can work for some people, it can be very dangerous to others. I tried it, but it didn't seem to work for me."
== You are welcome to elaborate on why you think it works for some and is "dangerous to others."
== The following is from a survey of parents of autistic kids. The percentages are impressive both from a stand point of effectiveness and safety.
(Note: some scientists think heavy metals are involved to some extent in a majority of autism cases).
ARI treatment parent ratings 2009
"Detox. (chelation)" 74% report "got better", 3% report "got worse", 23% report "no effect"
The 74% rating is the best of all of the many dozens of listed interventions. http://www.autism.com/pro_parentratings.asp
== DMSA was US FDA approved for lead in kids many decades ago. While the FDA has earned criticism about its role in Amalgam use, their process for approving medicines is quite rigorous.
"...It can be quite dangerous, especially in larger dosages. Any harmful and detrimental effects will probably show in the long run. Again, it depends on the individual."
== I agree about the risk when using larger doses. We've heard quite a number of unpleasant stories from those who got a mega dose of DMSA prior to a urine test for toxic elements.
== People need water to survive yet drown on it. It is important that the things we take are used safely. This is part of the reason for the debates over which protocol is the safest effective way to chelate out heavy metals.
"I chose to use natural and safer products to chelate the huge amounts of lead in my body: water and dry fasts, Green Clay taken orally, clay baths, apple pectin, kefir and colonic irrigations, humifulvate, milk thistle, lecithin, omega-3, megadoses of Vitamin C and lots of chlorophyll rich greens."
== This is a rare area where I trust something made in a lab more than something from our polluted environment. Take cilantro for example (yes I know you did not list it). People have been consuming cilantro probably for millennia; however until recent decades people did not have a mouth full of silver-mercury Amalgam fillings off-gassing Hg. Also cilantro now is being grown in a polluted environment where it can more likely pick up mercury (Hg).
== Some of the saddest stories I've heard have been from those who had a serious mercury problem and who used cilantro. The stories from pregnant women who used it are the saddest since it likely made it easier for the mercury to cross the placenta into her child.
== The risk of natural things picking up heavy metals from the environment is probably not obvious to most. The thiol/SH groups that attract mercury and some other heavy metals are present as the plant is growing. In this image you can see the SH groups of Lipoic Acid with space in between for the heavy metal ion. (Note: it is dangerous to take LA if pregnant and if not taking it according to a safe protocol). http://lpi.oregonstate.edu/infocenter/othernuts/la/lastructure.html
== This one reason I like Cutler's protocol. The primary chelator is lipoic acid (LA). LA is natural. The body naturally gets some from certain foods; however we take the synthetic form, ALA, that has not been grown in the environment where it could pick up Hg.
" It's hard work."
== So true, but it feels so good to have my health back in the normal range for my age after 15+ years of strange health problems. For two years I've been taking low, frequent doses of ALA + DMSA (Cutler protocol). I've gotten an 8% improvement in my bone density that previously was unresponsive to my doctor's medicine and supplements. My doctor was able to wean me off my ADD medicine. I've had less impressive gains in mood, memory, brain fog, tolerance for foods, etc.
== I wish I had started using DMSA + ALA decades ago.
I am glad that the Cutler Protocol worked for you. However, that doesn't mean that it will work for anyone or that anyone with a heavy metal problem has to use the Cutler Protocol. What I really do not appreciate about Cutler and the adherents of his protocol is that they believe they have found the one and only truth and the rest is rubbish.
I would have thought that it's self-evident why one person's medicine can be another person's poison. Each person's body and biochemistry is unique and different. Not all people have the same detoxification and regeneration capabilities, or the strength and endurance that the body requires during chelation. Not all detoxifying agents and substances will have the same effect on everyone.
Concerning the Cutler Protocol and chelation in general, I think it can be quite dangerous if the body's detoxification and elimination organs and systems (liver, kidneys, the intestine etc) are not able to function properly in order to eliminate the poisons that circulate in the blood during the ALA+DMSA rounds. Redistribution is also an issue with both ALA and DMSA (as it is with cilantro, which is why I said that not all things work the same on everyone).
Furthermore, DMSA can be toxic. It has been found to damage the kidneys and very possibly the liver, and to the best of my knowledge this has been backed up by scientific studies. The fact that it is FDA approved, doesn't really mean much. Many dangerous poisons were and still are approved by the medical establishment, but that doesn't make them a bit safer.
Finally, I do believe that there have been negative reports on the Cutler Protocol.
Therefore, the only wise thing to do is to proceed with extreme caution and always under medical supervision.
"I am glad that the Cutler Protocol worked for you."
== Thank you.
"However, that doesn't mean that it will work for anyone..."
== "Anyone?" Cutler's protocol is not really that new. He wrote his book, Amalgam Illness, back in 1999. It is based largely on existing protocols that can be found in medical text books. DMSA was FDA approved decades ago (1960's I think). I think DMPS goes back to the 1950s. Cutler's main contribution has been the use of lipoic acid along with DMSA or DMPS.
== Since his protocol has been around for over a decade there is a decent track record, for example:
Dr Amy Holmes, mother of an autistic child who greatly improved on treatments that included frequent dose chelation, did a small study on a hundred or so of her autistic patients.
Roughly 58% of children under 12 (75% < age 6) made "moderate" or greater improvement in less than a year. http://www.healing-arts.org/children/holmes.htm#results
Dr Dan Pompa attributes his nice improvement from his mercury problem to Cutler. He now teaches Cutler's protocol at his conferences for other doctors. He discusses this in the early minutes of this interview with Cutler. http://www.healthcentersofthefuture.com/DrCutler/
They are regular contributors to the yahoo Autism-Mercury group.
Of course Cutler claims that he greatly improved, including from the tremor that made it difficult for him to dial the phone.
"...or that anyone with a heavy metal problem has to use the Cutler Protocol."
== Very true. I encourage people to read and try to make a careful decision. I try to provide information, including lots of links to more information from a number of sources, Cutler, Boyd Haley, Mark Hyman, Dan Pompa, etc.
"What I really do not appreciate about Cutler and the adherents of his protocol is that they believe they have found the one and only truth and the rest is rubbish."
== True, we can be quite zealous. I ask for some understanding of our foibles. Consider that more than a few of us, including me, had been sick for over a decade with no hope from our doctors. The feeling of getting through the ups and downs of the first year of chelation is profoundly striking. You realize that your gains are really sticking--they are not just some short term improvements or something from the imagination. You now have both some nice improvement and the first real hope for a normal life in a decade or more! A person is bound to be excited by this and maybe a little too excited when talking about it to others.
== For folks like me who have been in several chelation groups for a couple of years, you read many dozens of sad stories from folks who did something or allowed their doctor to do something that caused a major setback. I suppose I'm rare in that two people in my circle of friends had this happen to them!!! I watched it happen to the woman I'm seriously dating when she took ALA inappropriately that came from one of her doctors!
== No half decent person with that experience--twice-- would fail to mention it to others!
"I would have thought that it's self-evident why one person's medicine can be another person's poison. Each person's body and biochemistry is unique and different. Not all people have the same detoxification and regeneration capabilities, or the strength and endurance that the body requires during chelation. Not all detoxifying agents and substances will have the same effect on everyone."
== I certainly agree that no two people are exactly the same. We are, however, all mammals and human beings. We really have more in common with each other biochemically than we have in contrast. Isn't is wise to take into account the things that we have in common?
If we put fire against a human's skin we can bet that bad things are going to happen.
Cutler has written something like, you are a mammal and you are taking a mercury chelator. You are going to excrete mercury.
"Concerning the Cutler Protocol and chelation in general, I think it can be quite dangerous if the body's detoxification and elimination organs and systems (liver, kidneys, the intestine etc) are not able to function properly in order to eliminate the poisons that circulate in the blood during the ALA+DMSA rounds...."
== I agree. I'm confident Cutler would agree, as long as you changed the word "properly" to "adequately." Many members of the FDC group have liver problems and so have to proceed with very low doses and liver support. We are fortunate that ALA sends most mercury (Hg) into the stool whereas, DMSA and DMPS sends most mercury into urine. So if a person has a problem with just one of the elimination routes, we can use a chelator that uses the alternate route.
"...Redistribution is also an issue with both ALA and DMSA (as it is with cilantro, which is why I said that not all things work the same on everyone)."
== So when a molecule of chelator drops some Hg that it mobilized--kicked up, there is a chance that the Hg will end up in a more vulnerable part of the body than from which it came.
==Cutler's protocol is designed to address this. This is the reason for the frequent dosing based on the half life of the chelator. By keeping blood levels of chelator rather stable, you increase the odds that the mobilized Hg will be picked up and safely chelated by a molecule of chelator in the next dose.
== When using well known chelators such as DMSA, DMPS and ALA, the half-life is known. We know how often we need to take it in order to keep blood levels reasonably stable. However, the cheltor that is in cilantro is not as well known. Does anyone know what the half-life of that chelator is? Are all varieties of cilantro equally potent? How can one safely use it?
"Furthermore, DMSA can be toxic. It has been found to damage the kidneys and very possibly the liver, and to the best of my knowledge this has been backed up by scientific studies."
== I think Cutler would agree that it *can* be dangerous if used improperly. People can drown on water, yet we need it for life. Everything is deadly if taken at some sufficiently excessive level or in some unsafe manner.
== The better question is, do we know how to use it safely and effectively? Fortunately DMSA has been around for many decades. Have there been more deaths from it than from aspirin and other OTC pain killers? Actually I'm not aware of any deaths from DMSA.
"The fact that it is FDA approved, doesn't really mean much. Many dangerous poisons were and still are approved by the medical establishment, but that doesn't make them a bit safer."
== Not even "a bit safer?" So you are okay with buying something off the street in Tijuana, Mexico? Obviously there is no way to know the long term effects when they are evaluating a new medicine, but DMSA, DMPS and ALA are not new. They've been in use for many decades. Cutler's protocol has been in use for over a decade.
"Finally, I do believe that there have been negative reports on the Cutler Protocol."
== Sure, of course it depends on what you mean by "negative reports." Most people feel a little worse while on a round of chelation, usually a three day round. They will usually have more fatigue and brain fog. Some don't sleep as well. However, when a person is taking modest doses, the sfx end about a half day after the end of the round. I just stop my round before going to bed on Sunday night. By the next morning I'm not in bad shape for work.
== Also folks need to get some basic supplements and provide support for their symptoms, especially endocrine symptoms. This is difficult because few new members understand what the adrenals are and fewer understand how much Hg affects adrenal and related systems. Often they are overly aggressive with doses and skimpy with supplement support. They'll become exhausted and need to take some time off for adrenal and thyroid testing and maybe some medicine. Gradually they bounce back.
== When I was beginning to look into chelation, I followed the cases of a half dozen new members of the chelation groups. While one or two might be playing games or too mentally ill to be accurate, you are going to get a feel for how folks are doing. Some people are so dreadfully sick. It seems to be hard for someone in that state to make up all of the things they post to the group on almost a daily basis.
== One of the most compelling cases I followed was that of the teen BillyMadison--I included a link above to his 1 yr update. Honestly when he came into the group I thought that he was mentally too sick to manage his recovery. I thought he was too far gone and would never get better from his very long list of symptoms. His early posts were erratic and mood unstable. He couldn't tolerate almost any supplements and was on very low doses of chelators. After a year, we could see that he actually had fairly good writing skills--better than me. He also reported some nice gains but he could have been making that up. I found the gradual improvements in his writing and the mood of his posts to be quite compelling. He clearly went from a mentally ill person to an obviously intelligent teen.
== While this is not scientific proof, it is yet another indicator of what is working for some people, and with 2000 posts per month from thousands of members, you have a decent number of people on which to base your decision.
"Therefore, the only wise thing to do is to proceed with extreme caution and always under medical supervision."
== I agree entirely. I visited my doctor every few months and got followup tests. Kicking up deadly heavy metals is no small matter. Neither is allowing them to continue to wreck your life!
== I chose Cutler's protocol because it seemed to be the safest, effective method to chelate lead, cadmium and mercury, the toxins that were most likely in play in my case. Two years later my health is back in the normal range for my age while not on any medications.
You said you've had less impressive gains in memory, mood, brain fog, and tolerance to foods. A shame, as those are the 4 things I really want to improve (plus weight loss - I've stalled again - and hypoglycemia if I don't eat enough ahead of time). And you've been doing this for 2 years. On the other hand, I recognize that you've been very sick before.
I'm annoyed, as I'm on month 6 and still have yet to see the "obviously much better" that many people report, unless I passed it a long time ago, like in the first month or two. I don't know. I'm on 50mg right now (I tried 60mg a couple rounds ago, and it had too many side effects, so I reduced it to 50mg).
I am thinking of doing a liver cleanse using an over-the-counter product sold in Whole Foods. Would that help? It's basically a mixture of herbs (milk thistle, which I take everyday as it is, and many other things like burdock root and such). Would the liver cleanse help with detox, or maybe I should do it anyway since I'd been detoxing so long that I'd be able to make some gains here? I want to improve my health as much as possible.
I do sometimes feel noticeably better than before - I hop this one fence one-handed almost every time I go for a walk, and a couple nights ago, I spontaneously started jogging for nearly a full block while going for my walk. Sure I was panting a LOT afterwards, but I still did it, and felt the urge to do it. I guess that means progress, right?
"You said you've had less impressive gains in memory, mood, brain fog, and tolerance to foods...."
== I've had gains in those areas which I appreciate very much. It is just that those gains are not as impressive to others as an 8% improvement in bone density that was previously unresponsive to my doctor's medicine and supplements. That is something that is well documented--broken leg without contact at age 43 plus subsequent DEXA scans. Also being weaned off of my last medication (Adderall) is also somewhat impressive since the doctor was involved in it.
== The better "tolerance to foods" is mostly in the area of sweets--reactive hypoglycemia-like symptoms that I've had for 15 yrs. I can now cheat at Christmas without badly "crashing" and looking like a stupid space cadet.
"I do sometimes feel noticeably better than before..."
== Honestly much of my first 10 months I spent wondering if I was just having a good week or if I was imagining one improvement or another. Ups and downs during the first year are common for people. They'll get some gains then overdo it with dosing and have a setback with candida or adrenals, etc. It was not until about 10 months when it was really clear that I was indeed getting better and that the gains were not some temporary fluctuation. It was a wonderful time of my life.
== I'm sorry I don't have any quick fixes for you. Cutler discourages us from using Liver Cleanses since many of us have liver problems and the cleanse might have something in it that will be problematic. He has a few suggestions in his book including what you are taking.
== People who are sick enough that they are struggling to hold down a job often benefit from 3 yrs of chelation.