Topical glutathione? It's an interesting idea. Have you tried other methods of raising glutathione? It seems that there are several that have good impact.
I've found that N-acetylcysteine (NAC) seems to have a profound effect on me, so I'm guessing it does a pretty good job of raising glutathione levels.
I haven't tried whey protein, but supposedly it's another good precursor for raising glutathione levels. Also, ALA (alpha lipoic acid, present in things like chia and flax seed) helps. And, rather interestingly, silymarin (from milk thistle) "has also demonstrated an ability to replenish glutathione levels in lab rats". Anyone find that interesting in that we're talking about liver-related function (detox)?
The next thing I'll be looking into more closely is what glutathione S-transferase
(GST) is and how it works and whether raising levels of it is also useful. At first blush it seems that GST is needed to help glutathione to perform. (This is why I was reviewing coffee enemas
— palmitic acid up the butt apparently stimulates GST activity.)