I have been on this forum for years, but switched to the parasites
forum because of the nature of my own disease.
After many years of researching myself and others from around the world, in is conclusive that these problems are more complex than humanity can even grapple with. It is no wonder doctors don't have much a say--nobody really knows the exact nature of chronic health conditions, unless they are easily defined by the current system (for that, it must reach acute status in most cases).
So, in my own case, I have a yeast problem for certain.
It is easily identified in stool by the shear numbers, never mind the symptoms.
It is not of the candida variety as far as visual inspection and colonization is factored.
It is parasitic, and can change morphology. It's survival and proliferation is a result of biochemical conditions in the gut,probably higher than normal PH, due to low stomach acid.
These conditions could be from lifestyle hereditary, and immune type conditions.
Nevertheless, the parasite
is a big problem.
Here is how it works: it targets specific cells of the body, and causes those cells to react. The reaction creates ideal environment for parasite
survival. It maintains a specific phenotype in the body, depending on where it is. This makes identification difficult. It can look like something different considering where in\on the body it is located.
The immune system reaction is low-key amplification, much like an allergy. So, essentially, the thing you are allergic to, exists inside\outside of your body continuously. You eventually develop a kind of tolerance, but have symptoms which cycle--because THEY cycle.
They can and do have physiological control over some cellular transduction pathways, so it has limited but certain control of body function.
Genetic analysis of the parasite
shows 100% compatibility with plasmodium falciprum which is malaria.
This is where it becomes complicated (if I haven't lost you already)!
It suggests that malaria was at one time related to a yeast.
Maybe I had malaria in the past, it cleared, but maintained it's existence in naturally occurring yeast cells in the gut
or the yeast is itself a relative of malaria (who knows).
The processes of cellular infection can be microscopically observed; the very small contents of the larger yeast cells will migrate and invade target cells, and aggregate to produce larger structures within the cell. Internal cell defence mechanisms are activated, but do not affect the invader portion. Collateral cells go nuts, and release copious amounts of defence granules (toxic proteins)which likely contribute to symptoms experienced by host.
The target cells die, and the parasite (components of)will remain in these cells which slough off. Dandruff is a good example, where the scalp cells have to shed to remove the parasite, thus the parasite moves back into environment where it will eventually phenoswitch into a form that is better suited for external environment, or even be picked-up by a susceptible host.
There you have it. Feels good to publish to people who may actually care!