Methyl Mercury Increases Intracellular Ca2+ and Inositol Phosphate Levels in Cultured Cerebellar Granule Neurons
This is kinda confusing. Inositol phosphate is supposed to help with mercury toxicity in the human body, yet methyl mercury increased the production of them? I'm guessing maybe its a defence mechanism. Then again, if mercury caused the body to produce more IP, why the need to suppliment?
As you can tell, I'm obviously no chemist. Nor am I too savvy with the chem lingo. Can you try to educate us in why you think supplimenting IP6 will help with mercury toxicity in layman's terms?
I've been aware that IP-6 has been shown to increase NK cell activity in the human body, so supplimentation can have very good results for all kinds of ailments caused by infection by viruses and other bugs by boosting the body's immune system. What I don't understand is how it would help excretion of stored mercury and other heavy metals. Please teach us what you have learned about this... in layman's terms. :)
EDIT: After some further reasearch on Inositol Phosphates I still havent found out how IP-6 removes heavy metals. Still, many sorces site that it can and does remove heavy metals including mercury, though most notably free iron and certain minerals. Seeing that there are all these benifits, particularly for the heavy metal toxic and immune compromised, sounds like a win win situation to me. Even if it doesn't pull out as much mercury as we would like, there will be positive effects from taking this regularly(unless you are deficent in iron). Also, seeing that this is a natural substance as opposed to syntetic chemicals as DMPS DMSA it should be be reletivly gentle compaired to the altenatives.
I wish there was a bit more information out there about the usage of IP6 for detoxing mercury. We know its effective on excess iron, but how effective is it with pulling out mercury stored in tissue. Will it cross the BB barrier? Is there a redistribution risk?
So far i think IP-6 sould be a good addition for heavy metal detox. Especially for those with high iron, but I'm not sure if it can replace DMSA or DMPS to target mercury elimination. I'm definatly going to try out the IP6 before starting on DMSA.