Blog: BV - Bacterial Vaginosis
by #42412

The 'promise' of BufferGel

If only I could find out when they're going to release it!

Date:   9/14/2006 8:39:46 AM   ( 11 y ) ... viewed 8399 times

Microbicides 2000, March 13-16, 2000, Washington DC Abstract Number A07.

BufferGelTM Favors In Vitro Growth of Lactobacilli While Inhibiting BV-Associated Organisms

Boskey, E.1, A. Jansen1, M. Merski1, K. Whaley1,2, T. Moench2, and R. Cone1,2. 1Johns Hopkins University and 2ReProtect, Inc., Baltimore, MD 21218

Vaginal microbicides should not be detrimental to lactobacilli. Lactobacilli produce broad-spectrum microbicides - including lactic acid and H2O2 - that have been shown to inactivate many sexually transmitted disease pathogens in vitro. Bacterial vaginosis (BV), during which there is an increased vaginal pH (>4.5), a loss of lactobacilli, and an overgrowth of other bacteria, is a significant risk for pre-term labor, amnionitis, pelvic inflammatory disease and HIV acquisition.

BufferGel™, an acidic polymer gel being developed as a vaginal spermicidal microbicide, is intended to buffer the vagina to
All lactobacillus spp. examined demonstrated some growth at pH 4 and significant growth at pH 5. In contrast, all BV-associated spp. were unable to grow at pH 4. Moreover, at acidic pH BufferGelTM had an additional inhibitory effect against several BV organisms. G. vaginalis, P. anaerobis, P. bivia, M. homonis and B. urealyticus, but not M. curtsii and M. mulieris, were all inhibited to a greater extent by 2 hour incubation in media acidified with BufferGelTM than in media acidified with HCl. These in vitro results suggest that BufferGelTM is not likely to disturb vaginal lactobacilli and may help prevent BV.

Elizabeth Boskey, Biophysics Department, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218.

Our Products
ReProtect's flagship product is the vaginal microbicide, BufferGel™. BufferGel™ is a buffering polymer that has demonstrated spermicidal activity and maintains the mild, protective acidity of the vagina. It is the first vaginal product designed to counteract the alkaline nature of semen. The vagina is naturally acidic (pH 4), which kills not only sperm, but also inactivates the pathogens that can cause many STDs, including HIV, herpes, syphilis and gonorrhea. The alkaline quality of semen neutralizes the protective acidity of the vagina for several hours after intercourse. This allows fertilization to occur since the acidity of the vagina would otherwise immobilize and kill sperm (see Abstracts and Manuscripts for additional information). Thus, BufferGel™ may prevent both unwanted pregnancy and STDs by enhancing a natural protective function of the vagina.

Add This Entry To Your CureZone Favorites!

Printer-friendly version of this page
Email this message to a friend
Bookmark this page/Add to Favorites or press Ctrl+D
DISCLAIMER / WARNING   Alert Webmaster

Share:  Facebook  MySpace  Digg  Reddit  StumbleUpon  Furl this page  Delicious  BlinkList  dzone  BlogMarks  Google

CureZone Newsletter is distributed in partnership with

Contact Us - Advertise - Stats

Copyright 1999 - 2017

0.125 sec, (2)

Back to blog!
Add Blog To Favorites!
Add This Entry To Favorites!

Comments (20 of 164):
Re: i have a quest… probe 4 y
Re: Years gone by.… kermi… 4 y
Re: Still waiting … Zippp… 5 y
Re: Still waiting … Zippp… 5 y
an easy cure Zippppp 5 y
What is bacterial … samir… 5 y
Re: Years gone by.… Karli… 5 y
Re: Femdophilus - … SnOwF… 5 y
Re: Unchartered wa… SnOwF… 5 y
Re: Recent Updates kermin… 6 y
Re: The Natural St… Caige… 6 y
Re: Pointless? purplelove… 6 y
Re: maybe you don'… adam1… 6 y
Re: maybe you don'… adam1… 6 y
Re: Recent Updates PiaBal… 7 y
Re: Effectiveness … #1299… 7 y
Re: Still waiting … Wanti… 9 y
Re: Vit C and Bloo… begon… 9 y
Re: Vit C and Bloo… simpl… 9 y
Re: Effectiveness … BV_Cu… 9 y
All Comments (164)

Blog Entries (12 of 49):
The 'promise' of BufferGel  11 y
Blessed Relief  11 y
RePhresh Vaginal Gel  11 y
Nothing to do with BV  11 y
Under Control  11 y
IUD Out!  11 y
Oh my Gosh!  11 y
IUD - seems to perpetuate th…  11 y
Pointless?  11 y
Femdophilus - Update  11 y
Here's a short bit  11 y
Just Started a new treatment…  11 y
All Entries (49)

Similar Blogs (10 of 185):
Minchus  by BeverlyDavis  64 h
Nursing in the Raw  by ren  3 d
ADD-ADHD Diagnosis,…  by CynthiaMadison  5 d
India Laparoscopy S…  by laceyalvarez  5 d
Black Cumin - Nigel…  by Blackseed Expert  11 d
Staying healthy wit…  by kirbykoopaling  12 d
Ormus Revealed  by greyalien  19 d
Jiaogulan-Tee ERKLÄ…  by gynostemma-tea  20 d
Jiaogulan Tee Bio v…  by gynostemma-tea  23 d
Warum Bioherby Jiao…  by gynostemma-tea  23 d
All Blogs (1,019)

Back to blog!

High Blood Pressure?
3 easy exercises drop blood pressure below 120/80 as soon as toda...

Clark Kidney Cleanse
Dr. Hulda Clark’s Kidney Cleanse with purest products! Great pric...

Natural Cancer Remedies
Cancer-proof your body with little known immune boosters!

Makes 100’s Silver Bottles
How to Makes Hundreds if not thousands of Bottles of Colloi...

Candida Complex™
How to get rid of candida, parasites, psoriasis, yeast infections nat...

Lugol’s Iodine Free S&H
J.Crow’s® Lugol’s Iodine Solution. Restore lost reserves.