The Pendulum Swings on Vitamin D
Date: 5/13/2018 11:04:23 PM ( 30 mon ) ... viewed 682 times
June 9, 2020 - Vitamin D plays a central role as an immune modulator -
"... Our immune system fights infections caused by bacteria or viruses with the help of messenger substances, antibodies and killer cells. Vitamin D plays a central role as an immune modulator and ensures that always enough, but also not too many immune cells wage war against the invaders."
May 13, 2028 -
Carolyn Dean MD ND responds to an Editorial from the February 15, 2018 issue of "American Family Physician" that advises: “Vitamin D Screening and Supplementation in Primary Care: Time to Curb Our Enthusiasm”. She says: "without a balanced viewpoint on vitamin D, it’s no wonder the public is so confused about this dietary supplement."
She continues: I wanted to title this blog “The Vitamin D Honeymoon is Definitely Over”, however, that’s an insult to people who have truly benefited from the introduction of vitamin D into their dietary supplement regimen. But I contend that these people for whom vitamin D is beneficial probably have enough magnesium on board to make it work properly. Click on this important link from VitaminDWiki for a chart showing that Magnesium is Vital to Vit D in 8 Places.:
The preamble to the study observed that “From 2000 to 2010, the volume of serum 25-hydroxyvitamin D (25-OH- D) tests reimbursed by Medicare increased 83-fold. In 2000, four out of 1,000 U.S. adults 70 years or older reported taking a daily vitamin D supplement of at least 1,000 IU, compared with four out of 10 in 2014—a 100-fold increase.”
Drug companies call the years after release of a new drug “post market surveillance” because they really don’t know how a drug is going to perform in the general population. After all, most studies are done on healthy people who are not on any other medications. Then those drugs, or in this case, high dose vitamin D, are given to a population subject to polypharmacy and magnesium deficiency and the results never quite match the studies.
The American Family Physician study determined that screening for vitamin D has virtually no established health benefits. The hard facts are that “The American Society for Clinical Pathology recommends against screening for vitamin D deficiency in the general population.” As for disease prevention “The U.S. Preventive Services Task Force found
insufficient evidence that vitamin D supplementation prevents cardiovascular disease, cancer, or fractures in community-dwelling adults.” Extensive meta-analysis “found only a handful of ‘probable’ relationships between serum vitamin D concentrations and clinical outcomes…”
What are some of the facts about vitamin D?
1. This study says vitamin D is a vitamin but it’s really a hormone so supplemental vitamin D doesn’t behave like a vitamin and doesn’t produce results like they think it should.
2. Vitamin D is actually a family of 7 different forms of D, much like vitamin C complex and the 8 tocopherols and tocotrienols of vitamin E.
3. 25-hydroxyvitamin D (25-OH- D), the standard test for vitamin D, is not even the active form, so how can that give us an accurate reading of active vitamin D in the body?
4. The original wildly speculative observations were not born out in later clinical trials.
5. Physicians misinterpret serum 25-OH- D concentrations of 20 to 30 ng per mL (50 to 75 nmol per L) as representing a deficiency that requires correction, whereas the National Academy of Medicine considers 97.5% of individuals with levels greater than 20 ng per mL to have adequate vitamin D for bone health.
6. Screening for vitamin D deficiency leads to hundreds of millions of dollars wasted in unnecessary testing costs annually.
7. Low-level daily supplementation with calcium and vitamin D can increase the risk of kidney stones. Magnesium deficiency plays a large and unrecognized role in these results.
8. High monthly doses of vitamin D increased the risk of falls in a randomized controlled trial of older adults with vitamin D deficiency.
9. The National Academy of Medicine says vitamin D intakes above 4,000 IU per day may cause renal impairment, hypercalcemia, or vascular calcification. Some of this damage may be due to the synthetic nature of high dose vitamin D, which creates toxic metabolites.
Instead of high dose vitamin D, I recommend a well-absorbed food-based fermented cod liver oil/butter oil called Blue Ice Royal. Otherwise, take vitamin D 3, but never more than 1,000-2,000IU daily. Always make sure you have adequate pico-ionic magnesium when you take vitamin D.
Carolyn Dean MD ND
The Doctor of the Future®
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