Blog: Boost Your Glutathione Levels
by Quinta_Essentia

Schisandra Berry Heals Liver, Raises Glutathione

Schisandra Berry Heals Liver, Raises Glutathione

Date:   2/3/2009 2:26:12 PM   ( 12 y ) ... viewed 3630 times

this study showed that a schisandra berrry extract known as schisandrin protects liver cells against toxins and raises glutathione levels significantly. it also says that '(-)Schisandrin B' is more effective than '(+)Schisandrin B' in raising glutathione levels, but i have no idea what that means! apparenlty the negatively charged schisandrin is more potent than the positively charged shisandrin. would you negatively charge your herbs? something to look into.

Effects of Schisandrin B Enantiomers on Cellular Glutathione and Menadione Toxicity in AML12 Hepatocytes

Department of Biochemistry, Hong Kong University of Science and Technology, Hong Kong, SAR, China

Pharmacology 2006;77:63-70

Effects of schisandrin B enantiomer ((+)Sch B and (-)Sch B) treatment on the reduced cellular glutathione (GSH) level and susceptibility to menadione-induced toxicity were investigated and compared in AML12 hepatocytes. (+)Sch B or (-)Sch B treatment at 6.25 µmol/l produced a time-dependent change in cellular GSH level, with the maximal stimulation occurring 16 h after dosing. (+)Sch B/(-)Sch B pretreatment for 16 h dose-dependently protected against menadione toxicity, with the maximum degree of protection observable at 6.25 µmol/l and the extent of protection afforded by (-)Sch B being larger than that of (+)Sch B. The cytoprotection was associated with a parallel enhancement in cellular GSH level in both non-menadione (control) and menadione-intoxicated cells.

While the GSH depletion produced by buthionine sulfoximine/phorone treatment largely abrogated the cytoprotective action of (+)Sch B/(-)Sch B, it almost completely abolished the GSH-enhancing effect of (+)Sch B and (-)Sch B in both control and menadione-treated cells. Both (+)Sch B and (-)Sch B treatments increased the GSH reductase activity in control and menadione-treated cells, with the stimulatory action of (-)Sch B being more potent than that of (+)Sch B in the control condition. (+)Sch B and (-)Sch B also enhanced the gamma-glutamate cysteine ligase activity in menadione-intoxicated cells. The results indicate that (-)Sch B is more effective than (+)Sch B in enhancing cellular GSH and protecting against oxidant injury in hepatocytes.

Add This Entry To Your CureZone Favorites!

Print this page
Email this page
DISCLAIMER / WARNING   Alert Webmaster

CureZone Newsletter is distributed in partnership with

Contact Us - Advertise - Stats

Copyright 1999 - 2021

0.266 sec, (2)

Back to blog!
Add Blog To Favorites!
Add This Entry To Favorites!

Comments (15 of 17):
Re: MSM Raises Glu… riham… 15 mon
Re: How to Superch… holys… 5 y
Re: Oral Glutathio… #2006… 5 y
Re: How to Superch… Ronen… 8 y
Re: How to Superch… #1341… 10 y
Re: How to Superch… gondo… 10 y
Re: How to Superch… Tizon… 11 y
Re: Glutathione Ki… Neo..… 12 y
Re: Glutathione Ki… Quint… 12 y
Re: Glutathione Ki… Neo..… 12 y
Re: Betaine for Gl… Quint… 12 y
Re: Betaine for Gl… #7697… 12 y
Re: Milk Thistle R… grzbe… 12 y
Re: Milk Thistle R… Quint… 12 y
Re: Milk Thistle R… grzbe… 12 y
All Comments (17)

Blog Entries (11 of 19):
Schisandra Berry Heals Liver…  12 y
Milk Thistle Restores Glutat…  12 y
Autism - a Glutathione and H…  12 y
Turmeric Boosts Glutathione …  12 y
#1 Cause of Liver Failure? I…  12 y
AIDS Tells the Story of How …  12 y
Diabetes Patients Suffer Fro…  12 y
Vit. C Raises Glutathione by…  12 y
Fenugreek Raises Glutathione…  12 y
Oral Glutathione Capsules ar…  12 y
Glutathione - Why It Is So C…  12 y
All Entries (19)

Similar Blogs (10 of 185):  by onlinerehabilative  24 h
uscomfort  by uscomfort9  28 h
uscomfort  by uscomfort9  44 h
uscomfort  by uscomfort9  47 h  by uscomfort9  66 h
Rehabilative  by onlinerehabilative  75 h
Buy Adderall Online  by onlinerehabilative  75 h
Jungle Safari And R…  by dishavarma  5 d
Internet ko dây 4G …  by myadhungtc4  7 d
Jeffery Waddell Blog  by JefferyWaddell  10 d
All Blogs (1,019)

Back to blog!

Purest Body Products
Sanctum Pure Body Products are so pure you could eat them (no gua...

Natural Cancer Remedies
Cancer-proof your body with little known immune boosters!

Wormwood Parasites Cleanse
Hulda Clark Cleanses

Lugol’s Iodine Free S&H
J.Crow’s® Lugol’s Iodine Solution. Restore lost reserves.

Free Natural Teeth Restoration!
The Powder that heals, protects, remineralizes

Better Than Colonics. Period.
Oxygen Detoxification for both small and large intestine...