Yes, this is a major problem for people with heavy metals like mercury, lead etc. CGally, what is the highest amount of probiotic strains that your currently taking?. Cutler recommends doses well above the average dose often stated. Have you considered VSL 3 with Custom Probiotics?. 480million bacteria per sachet for VSL 3 and 50billion for CP. Candida Overgrowth will never go until their's a drop in heavy metal burden. If you have a leaky gut as well, it would be recommended to treat the gut whilst chelating. Have you considered looking into the GAPS Diet. The introduction to the GAPS Diet has probably one of the best processes for healing a leaky gut "if" you have one with Candida Overgrowth .