I had the mirena taken out when it started to feel like my throat was closing. I had had problems with diarrhea once a month for 6 months after changing from ortho tricyclen pills to the low dose ortho tri cyclen. At that time my obgyn told me that progesterone affects smooth muscle. Your esophagous and intestines are made of smooth muscle and he said this was probably causing the diarrhea. Had the mirena put in and was fine until a year later when my throat started to feel like it was closing. Had it out and lost 20 pounds in 5 weeks. Could eat barely anything. I have a blood clotting disorder and was also told Mirena is good birth control for this condition because it's not sysytemic. I now know this is not true. You should not have the mirena with this condition. It has been over 2 years now and my digestion is fine.