CureZone
Old Format -> CureZone.INFO
Potential benefits of niacin & niacinamide on the liver detox process
  • Potential benefits of niacin & niacinamide on the liver detox process   Dquixote1217   6y  5,132  C  
    This is my avatar. Click here to see my profile.
    Dquixote1217
    Date: 11/4/2009 1:15:46 AM   ( 6y ago )   Hits:   5132

    One of my forum members on Yahoo told me that she was taking products that included both niacin and niacinamide and wondered if it was safe to take both at the same time. I had to do a little research to find the answer, and what I found was that it appeared to be not only safe in most instance, but perhaps beneficial as well due to the effects that niacinamide has on Phase 1 of the liver detoxification process and niacin has on Phase 2.

    "Simply speaking, the body's natural liver detoxification process involves two steps; Phase 1 and Phase 2. A toxin initially enters Phase 1, the P-450 cytochrome system, and is reduced to smaller fragments. These fragments then progress to Phase 2, where they are bound to molecules such as glutathione, glycine and sulfate. This process creates a new non-toxic molecule that can be excreted in the bile, urine or stool.

    In effect, Phase 1 either directly neutralizes a toxin, or modifies the toxic chemical to form activated intermediates which are then neutralized by one of more of the several Phase 2 enzyme systems. In Phase 1, a toxic chemical is converted into a less harmful chemical. This is achieved by various chemical reactions (such as oxidation, reduction and hydrolysis), and during this process free radicals are produced which, if excessive, can damage the liver cells. Antioxidants reduce the damage caused by these free radicals. If antioxidants are lacking and toxin exposure is high, toxic chemicals become far more dangerous. Some may be converted from relatively harmless substances into potentially carcinogenic substances.

    One or both detoxification phases can be inefficient or overloaded. A particularly damaging combination in an ill person is an excessive overload of toxins coming into Phase 1, with an inefficient Phase 2. In some cases this combination is believed to be the cause of marked environmental sensitivities, drug intolerances and interactions that characterize many chronic fatigue and fibromyalgia patients."

    http://www.diagnose-me.com/treat/T355489.html

    Niacinamide slows down phase 1, while niacin speeds up phase 2.  Niacin is also known as inositol hexanicotinate, vitamin B3 and nicotinic acid.

    As an interesting aside, there was a study last year at I believe Caltech Berkley, where they used high doses of niacinamide with 100% success in reversing the rodent equivalent of Alzheimer's.  Naturally, the researchers cautioned against anyone trying to do the same thing with humans and of the dangers of taking supplements - despite the fact that niacin and niacinamide have a virtual 100% safety record.  I believe that the proper interpretation was to not take any such supplements until they can produce a patentable version to market.

    All the best,

    DQ

     
    Printer-friendly version of this page Email this message to a friend
    Alert Moderators
    Report Spam or bad message  Alert Moderators on This GOOD Message
  • How can I view entire discussion thread on a single page?

    How can I expand all forum messages on a single forum page?


     

    Donate to CureZone


    Terms of Service - Privacy Policy - Spam Policy - Disclaimer - Guidelines & Rules

    CureZone Newsletter is distributed in partnership with www.netatlantic.com


    Contact Us - About - Advertise - Stats

    Copyright 1999 - 2015  www.curezone.org

    0.048 sec, (2)

    I cleansed my colon
    Naturally In Just 4 Short Days.


    Achieve Soft, Amazing Skin!
    This breakthrough invention will bring out the shine in yo...


    Cure Arthritis
    Here’s a simple, easy natural strategy to cure arthritis in 21 days



    High-Voltage Colloidal Silver
    I finally found a colloidal silver made with high voltag...


    Herbal Tinctures and Supplements
    Hulda Clark Cleanses


    ClarkFx Parasite Tincture
    Enhanced all in one Parasite Cleansing Tincture according to...



    What Causes Anger?
    Anger is all about control and/or not being in control. It is the o...


    Detoxify and Cleanse Naturally
    Drink ionized alkaline waters medically proven health b...


    Natural Cancer Remedies


    Royal Tea
    Keeping extraordinary people regular for 15 years! Get 10% off your first or...


    Kill Parasites Naturally
    How to Kill Parasites Naturally & Feel Great in 30 Days or Le...


    Cures Common Diseases
    Millions of antioxidant ions boost immune system function curing...


    Rose Laurel OPC Capsules
    15% Off With Curezone Discount Code Of Lr001



    Lugol’s Iodine Free S&H
    J.Crow’s® Lugol’s Iodine Solution. Restore lost reserves.


    The Tesla Shield™
    The #1 Personal Energy Enhancement Device. Transformational Technolo...


    The Best Years in Life
    Naturally live longer, healthier and happier and avoid mainstre...


    Em-Pro Probiotic
    2/3 of your immune system reside in your gut


    Best Enzymes?
    Probiotics with prebiotics and enzymes.


    Your Ad Here