CureZone
Old Format -> CureZone.INFO
Potential benefits of niacin & niacinamide on the liver detox process
  • Potential benefits of niacin & niacinamide on the liver detox process   Dquixote1217   7y  5,736  C  
    My Avatar. Click to see my profile.
    Dquixote1217
    Date: 11/4/2009 1:15:46 AM   ( 7y ago )   Hits:   5736

    One of my forum members on Yahoo told me that she was taking products that included both niacin and niacinamide and wondered if it was safe to take both at the same time. I had to do a little research to find the answer, and what I found was that it appeared to be not only safe in most instance, but perhaps beneficial as well due to the effects that niacinamide has on Phase 1 of the liver detoxification process and niacin has on Phase 2.

    "Simply speaking, the body's natural liver detoxification process involves two steps; Phase 1 and Phase 2. A toxin initially enters Phase 1, the P-450 cytochrome system, and is reduced to smaller fragments. These fragments then progress to Phase 2, where they are bound to molecules such as glutathione, glycine and sulfate. This process creates a new non-toxic molecule that can be excreted in the bile, urine or stool.

    In effect, Phase 1 either directly neutralizes a toxin, or modifies the toxic chemical to form activated intermediates which are then neutralized by one of more of the several Phase 2 enzyme systems. In Phase 1, a toxic chemical is converted into a less harmful chemical. This is achieved by various chemical reactions (such as oxidation, reduction and hydrolysis), and during this process free radicals are produced which, if excessive, can damage the liver cells. Antioxidants reduce the damage caused by these free radicals. If antioxidants are lacking and toxin exposure is high, toxic chemicals become far more dangerous. Some may be converted from relatively harmless substances into potentially carcinogenic substances.

    One or both detoxification phases can be inefficient or overloaded. A particularly damaging combination in an ill person is an excessive overload of toxins coming into Phase 1, with an inefficient Phase 2. In some cases this combination is believed to be the cause of marked environmental sensitivities, drug intolerances and interactions that characterize many chronic fatigue and fibromyalgia patients."

    http://www.diagnose-me.com/treat/T355489.html

    Niacinamide slows down phase 1, while niacin speeds up phase 2.  Niacin is also known as inositol hexanicotinate, vitamin B3 and nicotinic acid.

    As an interesting aside, there was a study last year at I believe Caltech Berkley, where they used high doses of niacinamide with 100% success in reversing the rodent equivalent of Alzheimer's.  Naturally, the researchers cautioned against anyone trying to do the same thing with humans and of the dangers of taking supplements - despite the fact that niacin and niacinamide have a virtual 100% safety record.  I believe that the proper interpretation was to not take any such supplements until they can produce a patentable version to market.

    All the best,

    DQ

     
    Printer-friendly version of this page Email this message to a friend
    Alert Moderators
    Report Spam or bad message  Alert Moderators on This GOOD Message
  • How can I view entire discussion thread on a single page?

    How can I expand all forum messages on a single forum page?


     

    Donate to CureZone


    Terms of Service - Privacy Policy - Spam Policy - Disclaimer - Guidelines & Rules

    CureZone Newsletter is distributed in partnership with www.netatlantic.com


    Contact Us - About - Advertise - Stats

    Copyright 1999 - 2016  www.curezone.org

    0.082 sec, (2)

    Natural Cancer Remedies


    High Blood Pressure?

    How 3 easy exercises drop blood pressure below 120/80 as soon a...


    Cure Skin Diseases Naturally
    Cures all common skin disorders fast and safely with no s...


    ”I Cured My Candida”
    Eliminate Candida Symptoms Within Hours!


    What’s Fatty Liver Disease
    Who Is at Risk for NAFLD & What Are the Symptoms? Read This...



    Fast Easy Weight loss
    Drop pounds daily drinking antioxidant detox ionized water which...


    Purest Body Products
    Sanctum Pure Body Products are so pure you could eat them (no gua...


    Heart Worms?
    Hulda Clark Cleanses


    Medically Proven Anti Diabetic Benefits
    Electrolyzed drinking water significantly redu...


    Liver Cleanse
    Eliminate any foreign substances that may be trapped in your liver.


    Cancer Curing Water
    Millions of medically proven antioxidant ions eradicate cancer cel...



    Eliminate Parasites Now!
    How to Eliminate Parasites in 30 Days or Less


    O-P-C (oleander Capsules)
    Boost Your Immune System For Healing HIV, Cancer, Hep-C


    Liquid Weight Loss
    Lose weight fast with naturally detoxifying antioxidant cleansing l...


    20lbs lost drinking water
    Lose 20 lbs drinking millions of antioxidant detoxifying ion...


    Detoxifying drinking water!
    Internal cleanse with millions of antioxidant ions in ever...


    Pure High PPM Antioxidants
    Bring your body back to perfections with Pure Colloidal Sil...


    Anti Cancer Water
    Drink millions of medically studied and proven anti cancer ions in e...



    Proven Cancer, HIV and Hep-C Remedy
    Proven natural remedy for cancer, HIV, Hep-C and m...


    Best Enzymes?
    Probiotics with prebiotics and enzymes.


    Best Candida Cure
    The only clinically proven candida cure with a 100%guarantee


    The Tesla Shield™
    Transformational Technology For Mind Body And Soul.


    Lugol’s Iodine Free S&H
    J.Crow’s® Lugol’s Iodine Solution. Restore lost reserves.


    Oxygen Rich Water Detoxifies the body
    Detoxify and experience Weight Loss with Oxygen ...


    -Orp Detox & Cleanses Internal Organs
    Cure Gout with Oxygen & lose weight by benefitin...


    -Orp Detox & Cleanses Internal Organs
    Cure Gout with Oxygen & lose weight by benefitin...


    -Orp Oxygen Cures Cancer
    Medical Research proves an abundance of Oxygen -ORP benefits ...


    Advanced longevity products
    Join the worlds leading co-researchers club


    Your Ad Here