Isolated Caprylic acid supplement is more likely to have side effects than the coconut oil. Ive heard high doses can be hard on the kidneys--(Maybe liver?) High amounts of coconut oil has caused diarreah/nausea for some. Anything that causes one to have diarreah for too long I would be cautious with.
Helmax-did that amount of coconut oil give you loose stools?
The experiment was done with the isolated caprylic acid. I wish he would have experimented with coconut oil. Ive never heard of coconut oil affecting friendly bacteria, but would like to do more research on it. The lipase enzyme might interefere with the cell wall of friendly bacteria if our flora cell wall is made of lipids.
Around the outside of the cell membrane is the bacterial cell wall. Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Bacterial cell walls are different from the cell walls of plants and fungi which are made of cellulose and chitin, respectively. The cell wall of bacteria is also distinct from that of Archaea, which do not contain peptidoglycan. The cell wall is essential to the survival of many bacteria, although L-form bacteria can be produced in the laboratory that lack a cell wall. The antibiotic penicillin is able to kill bacteria by preventing the cross-linking of peptidoglycan and this causes the cell wall to weaken and lyse. The lysozyme enzyme can also damage bacterial cell walls.
There are broadly speaking two different types of cell wall in bacteria, called Gram-positive and Gram-negative. The names originate from the reaction of cells to the Gram stain, a test long-employed for the classification of bacterial species.
Gram-positive bacteria possess a thick cell wall containing many layers of peptidoglycan and teichoic acids. In contrast, Gram-negative bacteria have a relatively thin cell wall consisting of a few layers of peptidoglycan surrounded by a second lipid membrane containing lipopolysaccharides and lipoproteins. Most bacteria have the Gram-negative cell wall and only the Firmicutes and Actinobacteria (previously known as the low G+C and high G+C Gram-positive bacteria, respectively) have the alternative Gram-positive arrangement. These differences in structure can produce differences in antibiotic susceptibility, for instance vancomycin can kill only Gram-positive bacteria and is ineffective against Gram-negative pathogens, such as Haemophilus influenzae or Pseudomonas aeruginosa.Interesting post: The lipid bilayer found in the fungal cell wall is critical for cell viability and pathogenicity. The lipid-coated fungi and other microorganisms are dependent on host lipids for their lipid constituents. This means that take them in from their surrounding environment. Disruption of the cell wall matrix results in a structurally-defective cell wall, rendering the fungal/yeast cell sensitive to osmotic lysis, macrophages, neutrophils, etc. Candida's lipid bilayer contains ergosterols that give it its strength. Undecenoic acid takes the place of the ergosterol and renders the fungal wall weaker and in more of a crystaline structure that is more fragile. Once the conversion has taken place, the weakened cell wall memebrane of the yeast cell is vulnerable to the immune system. The other supplement would be fine to take, although I would be a little concerned about the possible effect of caprylic acid. Wyss et al demonstrated more than 50 years ago that the greater the number of carbon atoms in the fatty acid chain, the greater the fungicidal activity, up to the point exceeding eleven carbon atoms, where solubility becomes the limiting factor. Undecenoic acid is an 11-carbon fatty acid. Caprylic contains 10 carbons and Lauric acid contains 12. Both have antifungal activity. Caprylic acid has toxicity associated with it. Lauric acid is a better anti-viral than an antifungal.
Caprylic acid is naturally found in the milk of cows, goats, and humans. If it is naturally found in milk of animals i dont see coconut oil having a big impact on killing friendly bacteria? Allthough, I havent seen any studies shown on high amounts of coconut oil affecting friendly bacteria?
Dont know how accurate these tests are because there using plant cultures rather than human strains. But it seems like it could give you some indication of how it might affect our friendly flora. Its hard to believe that oregano oil had no impact. I dont like oregano oil or GSE internally they seem to really irritate the gut producing too much mucus.
---Interesting how the isolated caprylic acid affected the yogurt strains more than the coconut oil. The concentrated caprylic acid must affect the cell membrane of bacteria more. Maybe that experiment partially explains why my brother gets diarreah+cramping after eating coconut oil. Maybe high amounts of coconut oil does affect friendly bacteria in some way shape or form? Maybe coconut oil would benefit those who have more dysbiosis. I would like to see the experiment done with undeconoic acid out of curiosity. I guess sometimes you just have to listen to your gut and your bowel movements.
----Im not surprised with the results on xylitol killing all the strains. Xylitol always upset my wifes gut when she ingested it. At Vitamin stores they put it into a lot of products thinking that it is a better alternative than regular sugar. If i was healthy i would much rather have the sugar than something that could be affecting my gut flora.
Thanks for the post
I think salt in general interferes with yeast causing it to self-destruct. I get die off from taking any kind of salt on a empty stomach. I dont like the idea of doing baking soda all the time because it be hard on the kidneys. Every now and then it seems to cause a pretty good die-off.