I'm not at all convinced that mastic gum has any effect on H. pylori in the human body. In many cases, I believe that IN VITRO (test tube) studies are devoid of any real worth. I lend more credence to IN VIVO studies. At best, it appears that the jury is still out on the effectiveness of mastic gum. In any event H. pylori is a very tough bug to kill. Even the "triple", and now, "quadruple" antibiotic "cocktails" frequently fail to eradacate H. pylori. How is H. pylori acquired, nobody knows? It is a nasty and poorly understood pathogen.
There are in vivo studies for both rats and humans.
But one major factor in the success of mastic will be stomach acidity. The active components in mastic are acids. Neutralization of these compounds by the ammonia secreted by the H. pylori can inactivate the properties just like the addition of alkaline substances to teas neutralizes their antioxidant effects from the acidic polyphenols.
So are you saying taking antacids will hurt mastic gum's effectiveness?
Because I'm also taking pepcid OTC...
Yes, antacids and acid blockers (proton pump inhibitors) can interfere with the ability of mastic to eradicate H. pylori. Even the H. pylori bacteria itself is acid sensitive, which is why it secretes highly alkaline ammonia to protect itself.
I guess if you have h. pylori, eating anything highly alkaline is not good?
It is not that simple since not all "alkaline" substances will neutralize the stomach acid. For example, nettle leaf is alkalinizing, but has really has little effect on neutralizing stomach acid.
On the other hand something like alkaline waters would directly neutralize stomach acid.
I have been taking mastic gum for 2 days now. Nothing yet.
I take 250mg 2x per day.
How long until I get some relief?
Two days is definitely not long enough to wipe out H. pylori. It can take weeks to months.
There is never a specific amount of time that any infection can be successfully treated since there are so many variables. For example, the extent of the infection, the person's immune status, the strength or amount of the compounds the person is taking to kill the infection, in the case of H. pylori the amount of stomach acid the person is producing, etc.
Something you can do to increase the effectiveness of the mastic gum though. I recommend taking the mastic combined with some licorice root, which also kills H. pylori, and a little yucca root that will increase the effectiveness of the other herbs.
In addition, the herbs should be increased to 3 to 4 times daily instead of twice daily. If the bacteria replicates faster than the herbs are killing it then you are not going to get anywhere.