Andy keeps saying that DMSA and ALA dissipate in your body at about the same rate, and that after three hours both are pretty much gone
Absolutely not true.
Remember, the term half-life refers to how long it takes for 50% of any substance to dissipate. So if substance X as a half-life of one hour, and you take 100 mg of it, that means after one hour 50 mg will be left
In order for a substance to dissipate in three hours, it's half-life would have to be 30 minutes. Let's say you take 100 mg of something, after 30 minute 50 mg is left, after one hour 25 mg, 1 1/2 hour 12.5 mg left, after two hours about 6 mg left, after two and half hours 3 mg left, finally after three hours there is only 1.5 mg still active
now the half-life of ALA is in fact about 30 minutes.
The half-life of DMSA is definitely not 30 minutes as Andy claims it is. Just do the research if you don't believe me. The half-life of DMSA is between 2.5 and 3.5 hours
look at this chart. The yellow line shows actual blood levels after one dose of DMSA. note that it takes about seven hours for there is a minimal amount of DMSA left in the blood. even after six hours there is still a considerable amount present in the blood
Dimercaptosuccinic acid (CHEMET) is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of DMSA is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments.
***Its elimination half-life is 2.5-3.5 h.***
DMSA can cross the blood-brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system
"now the half-life of ALA is in fact about 30 minutes."
"Andy keeps saying that DMSA and ALA dissipate in your body at about the same rate"
"The half-life of DMSA is definitely not 30 minutes as Andy claims it is"
First of all, Cutler never claimed the half life of DMSA to be 30 minutes. Nor did anyone on this forum. The error is in her misunderstanding of the implied half life of ALA in the context of chelation, and her faulty cross-reasoning that 1) since Andy claims DMSA and ALA dissipate at around the same rate, and 2) since she has researched ALA to have a half life of 30 minutes, that 3) Andy is indirectly stating DMSA also has a half life of 30 minutes. This is a disgrace to anyone with the most basic of reasoning faculties. But you want me to spell it out for you, and I will.
She is assuming that the half life of DMSA is being claimed by Andy as 30 minutes because of it "dissipating at about the same rate" as ALA. She did a web search and concluded the half life of ALA to be 30 minutes but didn't take into account the implication of ALA converting to DHLA (which does the chelation and has a half life of 3 hours). This implication was thoroughly and obviously understood by Cutler and clearly explained in his book. If he ever made a statement that DMSA and ALA dissipate at about the same rate, it is obviously referring to the contextual role of ALA as a chelator, in the form of DHLA (which has a half life of 3 hours). It is a petty communication syntax she is preying upon, but only because of her own misunderstanding and NOT on the fault of Andy or anyone elses reasoning.
And, thus, my point is that explaining how ALA quickly converts into DHLA, which is what does the chelating and has the half life of 3 hours, and how this always was understood by Cutler, effectively renders her entire post's reasoning obsolete because it takes a fundamental piece out of her equation. It was her misunderstanding to begin with.
The context of her post is that the *REAL* half life of DMSA is 2.5 to 3.5 hours, which is contrary to the supposedly *false* half life of 30 minutes (which only exists in her head and was never stated by anyone). Cutler never claimed that "after three hours both are pretty much gone." He is the one who advocated chelation dosing at the half life to BEGIN with, which, at that time, to the best of his knowledge was 4 hours for DMSA.
Today, DMSA's half life is readily found on any basic web search and is 2.5 to 3.5 hours. But unknown to Tizona, Cutler has already been advocating more frequent dosing. Once every 4 hours was the minimum frequency advised.
Thus, the conclusion that she is somehow exposing fraudulent information with her post is utterly ridiculous.
Does that clarify things for you?
Andy is simply a sound thinker and anyone who does the necessary research will find agreement with his protocol. He is not, as you both seem to think, worshipped as a "God" nor does he have a "following." He is merely an intelligent human being who contributed something useful to society, against criticism and name calling from the masses.
If either of you believe that bashing his protocol and calling him *delusional* some how make you heroes who stand out from the crowd, sorry, you have it backwards. You are the followers, and you are merely following the delusional thinking of the masses.
First off, if you can't see that many Andy CULTer's followers are religious fanatics just like Apple boys or any other person with undying loyalty to something they think "makes perfect sense", then I'm sorry to say you're one of those people.
People believe and die for their beliefs because they truly believe that they are right. No idiot straps a bomb to their chest unless their perception of their reality was that there was a real living God that will bless them for doing that deed. That being said, people who believe Cutler to be the ultimate truth and his protocol to be perfect believe so because they BELIEVE he is right. I don't question their belief. I question people who develop loyalty, belief and/or faith for a certain set of rituals, ideas or concepts and decides to submit completely to it without accepting that things and people change. That Cutler could be wrong or Christianity could be wrong, that newer technologies, newer trials and errors and experiences could prove what was thought to be TRUTH to be in fact erroneous.
The difference between you and me in seems, is not our beliefs in what is right but our attitude and reasoning in how to approach new information even if it means absolute change and upheaval of the current system. I have to say it's not surprising. The human being is trained and hardwired to do so. If you spent the past 30 years researching something and dedicating your entire LIFE to it, living and breathing said materials (can be applied to religion or any subject that affects your worldview) and someone came out with new research that completely destroyed your life's work and your reality, most people deny it or attack it as a defense mechanism against change and disturbance of their current reality and life as they know.
I'm sorry that at some point you read Cutler's work and it worked for you and that you decided to submit to him and his work or protocol and let your mind's antivirus down but I don't think that way. The Cutler method could work for me 100% but I'll say this, if he comes out with a new claim that I didn't agree with I would speak up and acknowledge what is the truth.
If you really want to argue reasoning and correct way of thinking, I suggest you study the trivium and really get into the history and methods of how the human brain's reasoning works and how the #1 mistake people make is to follow this procedure : a) gather information b) make conclusions c) finalize conclusion and end research.
When the correct way is a) gather information and concepts b) make conclusions while removing contradictions c) rhetoric. REPEAT. d) gather information e) Make NEW conclusions, remove contradictions. REPEAT.
Attachment to one set of rules or beliefs is never a good approach to learning my friend.
"First off, if you can't see that many Andy CULTer's followers are religious fanatics just like Apple boys or any other person with undying loyalty to something they think "makes perfect sense", then I'm sorry to say you're one of those people."
Of course I can see that other people are blind followers. For the most part, though, you have to keep in mind that majority of the people who are on the path of self healing are intelligent. Certainly intelligent enough to realize mercury amalgams are poisonous. You may actually be a reasonable thinker, I don't know for sure. However, by posting along with Tizona's troll-like misinformation, your calling cutler "delusional" sure makes you seem on the same level as these "fanatics" you so avidly despise.
"The difference between you and me in seems, is not our beliefs in what is right but our attitude and reasoning in how to approach new information even if it means absolute change and upheaval of the current system."
Where is the new information? This is about disproving Tizona's ridiculous claims, which I did.
"ALA is quickly converted by the body to DHLA. It is the DHLA that does the chelating and has the half life of 3 hours"
this is certainly not true. Both Lipoic acid and dihydrolipoic acid have the same half-life of about 30 minutes.
And again, you seem to be confused about what half-life means. Andy never said the half-life of ALA or DHLA is three hours. I have no idea where you got that from. If the half-life was truly three hours there would be plenty left in your system nine hours after taking it.
Andy claims that half-life of DMSA is between 35 and 40 minutes, which means it would be out of your system after about four hours. This is patently not true. the half-life of DMSA is in fact between 2.5 and 3.5 hours, which means even after seven or eight hours there is still quite a bit left in your system. which I clearly demonstrated in my post above.
"Andy keeps saying that DMSA and ALA dissipate in your body at about the same rate, and that after three hours both are pretty much gone."
He says the half life of DMSA is around 4 hrs but it will vary somewhat from person to person. Some will tolerate 5 hrs. I have reactive hypoglycemia and need to take food, other medicines, and chelators more frequently in order to experience a smooth consistent effect. I take DMSA every 3 hrs and ALA every 2.25.
He says the situation with ALA is more complex but most folks do okay by taking it every 3 hrs.
I know you've been a staunch supporter of Cutler for years now, and if you're doing better, I can certainly understand your devotion.
I did find a thread on the Phoenix Rising site, where people have been taking rather high and infrequent doses of ALA, plus they have fillings in their mouths, yet have been improving and one has recovered.
I wonder what your views would be on these people?