Virus Seen in Muscle from Chronic Fatigue Patients
By Will Boggs, MD
NEW YORK (Reuters Health) - A persistent enterovirus infection in muscles
may be to blame for some cases of chronic fatigue syndrome (sometimes called
fibromyalgia) and others with chronic inflammatory muscle disease, a French
They detected genetic material (specifically RNA) from enteroviruses in 20
percent of muscle biopsies from patients with chronic inflammatory muscle
diseases and 13 percent of patients with fibromyalgia/chronic fatigue
syndrome, but not from healthy volunteers.
The findings favor a persistent infection involving defective viral
replication as a cause of these conditions.
"The persistence of defective or infectious enteroviruses is well
established for a lot of organs," Dr. Bruno Pozzetto from the University
Hospital Center of Saint-Etienne, France, told Reuters Health.
Such infections have been documented in the heart, with possible involvement
in heart enlargement; in pancreatic cells, possibly linked to juvenile
diabetes; and in the central nervous system in association with a syndrome
that afflicts aging survivors of polio, the researcher explained. "However,
the link between these diseases, as well as chronic inflammatory muscle
diseases, and viral persistence is not clear."
Pozzetto and colleagues investigated the presence of enterovirus in skeletal
muscle biopsies from 15 patients with chronic inflammatory muscle diseases,
30 patients with fibromyalgia/chronic fatigue syndrome, and 29 healthy
subjects to test their hypothesis that skeletal muscle may play host to
persistent enteroviral infection.
Three patients with chronic inflammatory muscle disease and four patients
with fibromyalgia/chronic fatigue syndrome were positive for enterovirus
RNA, the team reports in the Journal of Medical Virology.
None of the muscle biopsies in this study contained a particular viral
protein, the researchers note, which "suggests a defective viral
It is too early to derive implications for treatment from these results,
However, he noted that so-called Coxsackie B viruses seem to play a key role
in persistent muscular infections. "To prevent this persistence, an
inactivated vaccine directed toward these viruses could be indicated."
Also, an antiviral agent called pleconaril, "acting during the early phases
of the viral cycle, could also be useful in muscular diseases clearly
associated with enterovirus." This is being tried in some cases of
heart-muscle enlargement, Pozzetto said, but "it is too early to answer for
SOURCE: Journal of Medical Virology, December 2003.
Having had catastrophic relapses in which my "Fibromyalgia" would cause a total blow-out of every past trauma over a short period of time, I had come to suspect a pathogen as the root cause. The Coxsackie B Virus already showed up on my research radar, so this confirmation by a French study is vitally important. Another French study years ago showed a laying down of Calcium in cases with a clinical presentation of neuro-muscular pain.
This earlier study was also done on a small group, eleven people, with the same painful protocol used here which demands "core samples" of muscle tissue. God bless those volunteers. The interface of this data may be that an infectious agent, apparently a poorly replicating form of Coxsackie B virus, causes inflammation.
The body will tend to lay down Calcium to sooth inflammation caused by cellular degradation. This can occur in any tissue group, and was first detailed by Dr. Larrian Gillespie as it attacks the urinary tract. Gillespie's book, "You Don't Have to Live with Cystitis" is an excellent primer on the "Leaky Cell" mechanism. Gillespie discovered there were amino acids, including Tryptophan in turkey, which aggravated "Leaky Cell," and has provided a low-pain diet in this book.
Needless to say, Calcium, the contractor mineral, can have a deleterious effect when laid down in, for example, any affected muscle or connective tissue. A treatment might demand that not only is the Coxsackie B Virus eliminated, which could be through drugs or electrical blood and lymph cleaning per the Beck research, but the removal of "trash" Calcium and cell healing.
Celery, containing organic Sodium, is quite effective in keeping Calcium in solution and removing bone spurs. It could help in Stenosis and intracellular Calcium. Magnesium levels, always lower when bound by Candida, need to be kept up, as with Apples, to keep Calcium in solution to enhance its being released by cell tissue when no longer needed--after the Coxsackie B Virus is whacked. "God bless us everyone."