I was taking 2000mg of niacin (inositol hexanicotinate) for acne and what I suspected was a candida infection and I began to experience something strange. First, my eyebrows began thinning as well spots in my hairline, I also gained weight, and began having cold intolerance. I suspect that I became hypothyroid but in trying to remedy my situation I'm trying to determine exactly what happened.
In my search, I've come across a lot of contradiction in terms of how niacin affects zinc, iron, and copper. Can anyone tell me with certainty how niacin interacts with these minerals?
I pretty sure I'm zinc deficient, it's just a matter of determining whether I'm copper or iron (and cofactors) deficient.
The problem isn't how it affects these things, especially when you use inositol hexanicotinate but which part of your liver gets taxed by it.
After a few years of playing with this; your best bet is to use Niacinamide first to synch your Phase 1+2 liver functions. Something like 3x1000mg per day will work for that, you could take a small amount of inositol hexanicotinate while doing this, maybe 500mg.
Once synchronized you could step it up but most likely won't have to. The thing to remember here is that this all works on your Krebs cycle and therefore may require more supplementation to help with the detox.
B2 helps, B1 also helps but will be eaten by your Candida, and supplements like Benfotiamine are available to help you past that.