Chances are if you are here, you probably already know about IP-6. If you don't, or perhaps just want to know a bit more, here's some information put together by Bill Sardi, the renouned medical/health reporter, who has penned several very informative books. We'd encourage you to visit his website, http://www.knowledgeofhealth.com
to learn more about his research.
With advancing age the human body harbors parasites, accumulates cellular debris, fats, and metallic minerals. In the later years of life accumulated iron and calcium cause tissues in the body to rust and calcify. The liver stores iron. The gall bladder and kidneys develop calcium and irons stones. Heart valves and arteries calcify and become clogged with cholesterol. The brain, retina and heart amass lipofuscin (ly-po-fusk-in) pigments. Parasites such as H. pylori (bacteria), Candida albicans (yeast), hepatitis and herpes viruses thrive as the human body begins to store extra iron with advancing age.
The question is how to reverse all of these aging and disease factors. Alternative medicine practitioners often suggest detoxification, liver cleansing, or chelation therapy to remove these elements from tissues. But such efforts are often over-promoted, poorly researched, expensive or sometimes ineffective.
There is a simple, economical and effective way of ridding the body of all of these undesirable organisms, debris and metals with advancing age --- IP6 rice bran extract.
IP6 is inositol hexaphosphate (also called phytic acid), which is found in every cell of the human body, is one molecule of inositol and six of phosphate and is found naturally in whole grains (bran), seeds and nuts. IP6 is known as nature’s master mineral chelator (remover).
IP6 is another of the many natural molecules that both conventional and alternative health practitioners continue to overlook. Researchers from around the world indicate they are searching for metal chelating agents to prevent or treat disease but fail to employ IP6 rice bran extract which is safe and economical. Conventional medicine’s narrow use of patented drugs rather than natural remedies blinds many health practitioners from the use of natural remedies such as IP6.
IP6, extracted from rice bran, is available as a dietary supplement and natural chelator of metals from living tissues. As a dietary supplement, IP6 is documented as a cleanser of arteries, the heart, brain, kidneys, liver, gall bladder (stones), and many other tissues. Here is the evidence for your review.
IP6 cleanses heavy metals
IP6 attaches to heavy metals such as mercury, lead and cadmium, as well as loose iron, copper and calcium. [J Agriculture Food Chemistry 47: 4714-17, 999] IP6 is a selective chelator -- it does not attach to potassium, sodium or magnesium, important electrolyte minerals required for heart rhythm. IP6 does not remove calcium from bones or iron from red blood cells. Once chelated (attached), these excess minerals are excreted via the urinary tract. [Crit Rev Food Sci Nutr. 35:495-508, 1995]
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IP6 cleanses the kidneys
Numerous scientific reports confirm that IP6 inhibits the formation of kidney stones and can be used to dissolve calcium stones in the kidneys once they are formed. [Scandinavian Journal Urology Nephrology 34: 162-64, 2000] IP6 is described as a “clear alternative in the treatment of calcium kidney stones.” [Anticancer Research 19:3717-22, 1999] Another study concludes that IP6 “may be a useful agent in the treatment of patients with kidney stones.” [Scand J Urology Nephrology 32:261-5, 1998]
While various studies confirm IP6’s ability to inhibit kidney stones, it goes unused by physicians. [Arch Esp Urology 52:305-10, 1999]
IP6 cleanses the heart
Researchers in Israel recently reported that methods are available to measure iron accumulation in the heart. Iron chelators such as IP6 would provide therapy for a heart weakened by excess iron. [Br J Haematology 125:545-51, 2004]
IP6 cleanses the arteries
One published report exclaimed that IP6 has an “extraordinary capacity” to inhibit calcifications throughout the body. [Anticancer Research 19:3717-22, 1999] IP6 can potentially remove calcium deposits from arteries. [International Journal Cardiology 33: 191-9, 1991] IP6 has been shown to significantly lower cholesterol in animals fed a cholesterol-enriched diet. [Anticancer Research 19:3699-702, 1999]
IP6 cleanses the liver
About a third of American adults have a condition called fatty liver. IP6 has been demonstrated to be a remedy for fatty liver. [Anticancer Research 19: 3695-98, 1999]
The liver is an organ that stores iron. Since iron is a growth factor for bacteria, fungi and virsuses, removal of iron from the liver may inhibit scarring caused by hepatitis. [Am J Gastroenterology 99: 286-91, 2004] Iron-restricted diets protect against liver damage in cases of chronic hepatitis C infection. [Hepatogastroenterology. 2002 49:529-31, 2002]
Removal of iron from the liver by periodic consumption of IP6 rice bran extract may be advantageous in liver disease.
IP6 cleanses the colon
Fiber is often promoted as a preventive measure against colon cancer. But not all types of fiber exhibit this protective property. Only the fiber found in whole grains (bran) that contains iron-binding IP6 prevents colon cancer. [Cancer 56: 717-18, 1985]
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IP6 cleanses the brain
Loose iron is involved in the onset and progression of brain diseases such as Alzheimer’s, Parkinson’s, Huntington’s disease and Frederich’s ataxia. [Ann N Y Academy Sciences1012:306-25, 2004] Metal removal (chelation) is proposed as a treatment for Alzheimer’s disease by its ability to dissolve beta amyloid plaques in the brain. [Journal Alzheimer’s Disease 6:291-301, 2004]
Neuromelanin is a brain pigment that control iron which may be overwhelmed with advancing age. A preliminary study using an iron chelator among Alzheimer’s patients produced some encouraging results, but concerns over the side effects of chelating drugs have limited further research. [Lancet Neurology 3: 431-34, 2004] However, IP6 has been found to be non-toxic in comparison with pharmaceutical chelators. [Environmental Molecular Mutagenesis 38:347-56, 2001]
Researchers are now poised to utilize iron chelators to prevent or treat age-related brain disease, but appear confused on how to proceed because of the terrible side effects posed by the use of prescription metal chelators.
IP6 is an overlooked chelator in the treatment of brain disease. Rats fed a diet rich in IP6 exhibit much lower iron levels in brain tissue. [J Trace Elem Med Biology15:221-8, 2001] When IP6 is added back into the diet of IP6-depleted animals, IP6 levels in brain tissues rise by 100 times. [Life Science 71:1535-46, 2002]
IP6 cleanses the gall bladder
Gallstones are composed of cholesterol, and in the later years of iron and calcium.
[Gastroenterology 76: 548-55, 1979] Children with inherited iron disorders exhibit increased risk for gallstones. [Acta Radiologica 40: 440-43, 1999] Removal of calcium and iron from the gall bladder may dissolve gall stones.
IP6 cleanses tissues of aging debris
Lipofuscin (ly-poh-fusk-in) is an aging pigment that accumulates in the brain, heart, retina and other tissues throughout the body. Oxygen and loose iron promote the accumulation of cellular debris called lipofuscin while iron chelators diminish it. [Free Radical Biology Medicine 33:611-9, 2002] IP6 as a potent mineral chelator could potentially remove lipofuscin deposits from aged tissues.
IP6 is an antibiotic
Iron encourages the growth of various parasites (bacteria, protozoa, viruses, fungi/yeast). [Microbial Pathogenesis 36:263-71, 2004; Clinical Infectious Diseases 25: 888, 1997] E. coli is a common pathogenic bacterium found in contaminated foods and water. In one animal experiment, when animals were intentionally infected with E. coli bacteria and given iron, all the animals succumbed. All the infected animals not given iron survived, underlining the importance of iron in the severity of infection. [Immunology 15: 581, 1968] Iron binders like IP6 can potentially be used in the treatment and prevention of infection. [Iron and Your Health, 1991]
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IP6 offers additional health benefits
There are additional heath benefits which may ensue from supplementation with IP6 rice bran extract. IP6 promotes DNA repair. [Cell 102: 721-29, 2000] Excess iron may have a role in the development of diabetes and IP6 may play a role in reversing diabetes. [Diabetic Medicine 21:798-802, 2004] IP6 also prevents blood clots. [Anticancer Research 19:3689-93, 1999]
IP6 is misunderstood
Unfortunately dietitians have been taught that IP6 is an anti-nutrient, that because of its mineral chelating properties it deprives the body of essential nutrients. Dietitians often fail to distinguish growing children, who have high calcium and iron needs, from adults who begin to accumulate excessive minerals with advancing age. Females experience delayed accumulation of iron because of monthly menstruation and avoid calcium overload by donating this mineral to their offspring during pregnancy and lactation.
While nutritionists have been taught that IP6 in whole grains and seeds suppress the bioavailability of minerals, when IP6 was added to the diet of mice it did not affect their absorption of iron or calcium. [Journal Nutrition 114: 1192-98, 1984; Journal Nutrition 111: 841-47, 1981] Another study concluded that IP6 has no negative effects on mineral status and that adequate amounts in the diet are “remarkable and must be favorably considered.” [J Trace Element Med Biology15:221-8, 2001]
I take 4 supplements C,I, R-lipolic Acid and IP-6. All you need the rest you get from food. Semper Fi Bill
Thank you for the post, I was going to read through old posts to try to find out more information about it. One of the problems I'm trying to figure out with taking it, is that it is supposed to be taken on an empty stomach, and away from foods. I take it first thing in the morning. I also don't know what dosage to shoot for. The one I have is from Jarrow Formulas, 500 mg, and it says:
Take 1-6 capsules per day on an empty stomach. DO NOT take at the same time of day as minerals or medications. IP6 is an efficient meneral chelater and therefore should be taken only on an empty stomach.
Also, I remember a post from Newport about pork tapeworm cysts, and he said Bromelain for the calcified cysts, and IP6. I'm trying to find the post again.
BTW--my father and brother were in the Marine's, headed on a ship to the Korean War when they got word the war had ended--went to Japan instead. I found out things I never knew about his time in the Marine's, when my Veteran daughter (Afghanistan) was talking to him about it. It was pretty cool, she dedicated a flag to be flown in honor of her Grandpa at the base she was at in AF, and then brought it home for him as a gift.
I do alot of reading on the forums, old posts and new. There's always something more to learn. So, even if I'm not posting, doesn't mean I'm not paying attention.
In fact...I just had a lightbulb go off tonight, and I hadn't considered it before. Lyme has continued to show up on the biofeedback, computer testing (and the Rocky Mountain Spotted Fever I knew I had 40 years ago from a tick)...Cat's Claw is supposed to help with Lyme arthritis, and I started taking it a few weeks ago for stiffness in my hips/lower back, as a test.
It is also supposed to help heal the gut, and with digestive issues.
It's an immune booster. That is what I hadn't taken into consideration before. It says that in people with auto-immune "diseases", that it is contraindicated. I've thought about the parasites/candida/bacterias etc taking over a body that has a weakened immune system...but I hadn't considered that if a body has an auto-immune disease
What I got, was just off the shelf at the drug store, but there's alot of good information on CZ if you search under "Samento". A specific, better quality type. I've found a couple of sources in my searches for where to buy it, and I want to give it a try.
I haven't had the stiffness in the hips that I had been having. We'll see if I notice a difference when I run out.
Celiac does run in families. I know my brother was told by MD's 25 years ago, that what he thought at the time might be scabies...was the rash from Celiac. Instead of giving up the gluten all this time, he's taken potent "blood disorder" pharma drugs that have done damage to his liver and thyroid. When I was diagnosed with the endoscopy/biopsy, he was adamant that no Dr had ever told him his rash was from Celiac..so he asked his Dr, and the Dr told him "of course it is, hasn't anyone ever told you that?"--they have, he just has chosen to not have to make the necessary changes and cut out the gluten.
Mom wasn't alive to test to see if it was from her side that we got it from...but I had dad do a blood test for it--and it came up "normal"....HOWEVER- just a few months ago, he did a saliva test for adrenal fatigue, and the ND had other things included in the test, including food allergies--his allergy to gliadin/gluten showed up 3x what mine is! He's just finding this out at the age of 78...also an allergy to eggs.
interesting that his blood test came up normal, and an allergy test is showing a mega reaction to gluten
it just proves to me that being tested is not as important as the results you get from trial and error experimentation
i say get tested to document your results, but do not rely on tests to find out what your body needs in order to feel better
if you want to feel better, talk to people who've eradicated the same symptoms that you have, to find out how how they got rid of them, buy a homeopathic repertory and find out what remedies match your symptoms, read anecdotal information about native herbs and experiment with the ones that have traditionally been used to eradicate similar conditions
but that requires risk taking behavior and the risk averse will continue to rely on procedural processes that are inherently limited
why anybody could have more confidence in a prescription issued on the basis of a test, more than how their body feels when they take an herb that matches their symptoms, is incomprehensible to me
it is good that your father is learning how to listen to his body
does he feel better now that he's quit eating eggs?
Just found this link to a load of articles on Samento and particular diseases. If it's TOA-Free, it's an immune system modulator not a stimulant. I'm doing Samento next. It's powerful stuff - 3 drops did me in. I think now that I've been on iodine for six months, though, that it'll be a much smoother ride.
I found through searching, that there's alot of information on the TOA-free Samento here on CZ too, and sources. I had just gotten the Cat's Claw off the counter at the drug store, but I want to order the Samento TOA-free.
Here's another interesting thing I've just been looking into too...Graviola (Sour Sop). I found a homeopathic on http://www.iherb.com
that has the graviola/cat's claw together.
HERBAL PROPERTIES AND ACTIONS
Main Actions Other Actions Standard Dosage
kills cancer cells
slows tumor growth
Infusion: 1 cup 3 times daily
Tincture: 2-4 ml 3 times daily
Capsules: 2 g 3 times daily
reduces blood pressure
Graviola is a small, upright evergreen tree, 5–6 m high, with large, glossy, dark green leaves. It produces a large, heart-shaped, edible fruit that is 15–20 cm in diameter, is yellow-green in color, and has white flesh inside. Graviola is indigenous to most of the warmest tropical areas in South and North America, including the Amazon. The fruit is sold in local markets in the tropics, where it is called guanábana in Spanish-speaking countries and graviola in Brazil. The fruit pulp is excellent for making drinks and sherbets and, though slightly sour-acid, can be eaten out of hand.
Tribal & Herbal Medicine Uses
All parts of the graviola tree are used in natural medicine in the tropics, including the bark, leaves, roots, fruit, and fruit seeds. Different properties and uses are attributed to the different parts of the tree. Generally, the fruit and fruit juice are taken for worms and parasites, to cool fevers, to increase mother's milk after childbirth, and as an astringent for diarrhea and dysentery. The crushed seeds are used against internal and external parasites, head lice, and worms. The bark, leaves, and roots are considered sedative, antispasmodic, hypotensive, and nervine, and a tea is made for various disorders toward those effects.
Graviola has a long, rich history of use in herbal medicine as well as a lengthy recorded indigenous use. In the Peruvian Andes, a leaf tea is used for catarrh (inflammation of mucous membranes) and the crushed seed is used to kill parasites. In the Peruvian Amazon the bark, roots, and leaves are used for diabetes and as a sedative and antispasmodic. Indigenous tribes in Guyana use a leaf and/or bark tea as a sedative and heart tonic. In the Brazilian Amazon a leaf tea is used for liver problems, and the oil of the leaves and unripe fruit is mixed with olive oil and used externally for neuralgia, rheumatism, and arthritis pain. In Jamaica, Haiti, and the West Indies the fruit and/or fruit juice is used for fevers, parasites and diarrhea; the bark or leaf is used as an antispasmodic, sedative, and nervine for heart conditions, coughs, flu, difficult childbirth, asthma, hypertension, and parasites.
Many active compounds and chemicals have been found in graviola, as scientists have been studying its properties since the 1940s. Most of the research on graviola focuses on a novel set of chemicals called Annonaceous acetogenins. Graviola produces these natural compounds in its leaf and stem, bark, and fruit seeds. Three separate research groups have confirmed that these chemicals have significant antitumorous properties and selective toxicity against various types of cancer cells (without harming healthy cells) publishing eight clinical studies on their findings. Many of the acetogenins have demonstrated selective toxicity to tumor cells at very low dosages—as little as 1 part per million. Four studies were published in 1998 which further specify the chemicals and acetogenins in graviola which are demonstrating the strongest anticancerous, antitumorous, and antiviral properties. In a 1997 clinical study, novel alkaloids found in graviola fruit exhibited antidepressive effects in animals.
Annonaceous acetogenins are only found in the Annonaceae family (to which graviola belongs). These chemicals in general have been documented with antitumorous, antiparasitic, insecticidal, and antimicrobial activities. Mode of action studies in three separate laboratories have recently determined that these acetogenins are superb inhibitors of enzyme processes that are only found in the membranes of cancerous tumor cells. This is why they are toxic to cancer cells but have no toxicity to healthy cells. Purdue University, in West Lafayette, Indiana, has conducted a great deal of the research on the acetogenins, much of which, has been funded by The National Cancer Institute and/or the National Institute of Health (NIH). Thus far, Purdue University and/or its staff have filed at least nine U.S. and/or international patents on their work around the antitumorous and insecticidal properties and uses of these acetogenins.
In 1997, Purdue University published information with promising news that several of the Annonaceous acetogenins were " . . . not only are effective in killing tumors that have proven resistant to anti-cancer agents, but also seem to have a special affinity for such resistant cells." In several interviews after this information was publicized, the head pharmacologist in Purdue's research explained how this worked. As he explains it, cancer cells that survive chemotherapy can develop resistance to the agent originally used as well as to other, even unrelated, drugs. This phenomenon is called multi-drug resistance (MDR). One of the main ways that cancer cells develop resistance to chemotherapy drugs is by creating an intercellular pump which is capable of pushing anticancer agents out of the cell before they can kill it. On average, only about two percent of the cancer cells in any given person might develop this pump—but they are the two percent that can eventually grow and expand to create multi-drug-resistant tumors. Some of the latest research on acetogenins reported that they were capable of shutting down these intercellular pumps, thereby killing multi-drug-resistant tumors. Purdue researchers reported that the acetogenins preferentially killed multi-drug-resistant cancer cells by blocking the transfer of ATP—the chief source of cellular energy—into them. A tumor cell needs energy to grow and reproduce, and a great deal more to run its pump and expel attacking agents. By inhibiting energy to the cell , it can no longer run its pump. When acetogenins block ATP to the tumor cell over time, the cell no longer has enough energy to operate sustaining processes—and it dies. Normal cells seldom develop such a pump; therefore, they don't require large amounts of energy to run a pump and, generally, are not adversely affected by ATP inhibitors. Purdue researchers reported that 14 different acetogenins tested thus far demonstrate potent ATP-blocking properties (including several found only in graviola). They also reported that 13 of these 14 acetogenins tested were more potent against MDR breast cancer cells than all three of the standard drugs (adriamycin, vincristine, and vinblastine) they used as controls.
The Annonaceous acetogenins discovered in graviola thus far include: annocatalin, annohexocin, annomonicin, annomontacin, annomuricatin A & B, annomuricin A thru E, annomutacin, annonacin, annonacinone, annopentocin A thru C, cis-annonacin, cis-corossolone, cohibin A thru D, corepoxylone, coronin, corossolin, corossolone, donhexocin, epomuricenin A & B, gigantetrocin, gigantetrocin A & B, gigantetrocinone, gigantetronenin, goniothalamicin, iso-annonacin, javoricin, montanacin, montecristin, muracin A thru G, muricapentocin, muricatalicin, muricatalin, muri-catenol, muricatetrocin A & B muricatin D, muricatocin A thru C muricin H, muricin I, muricoreacin, murihexocin 3, murihexocin A thru C, murihexol, murisolin, robustocin, rolliniastatin 1 & 2, saba-delin, solamin, uvariamicin I & IV, xylomaticin
Biological Activites and Clinical Research
In an 1976 plant screening program by the National Cancer Institute, graviola leaves and stem showed active toxicity against cancer cells and researchers have been following up on these findings since. Thus far, specific acetogenins in graviola and/or extracts of graviola have been reported to be selectively toxic in vitro to these types of tumor cells: lung carcinoma cell lines; human breast solid tumor lines; prostate adenocarcinoma; pancreatic carcinoma cell lines; colon adenocarcinoma cell lines; liver cancer cell lines; human lymphoma cell lines; and multi-drug resistant human breast adenocarcinoma. Researchers in Taiwan reported in 2003 that the main graviola acetogenin, annonacin, was highly toxic to ovarian, cervical, breast, bladder and skin cancer cell lines at very low dosages saying; “. . . annonacin is a promising anti-cancer agent and worthy of further animal studies and, we would hope, clinical trials.”
An interesting in vivo study was published in March of 2002 by researchers in Japan, who were studying various acetogenins found in several species of plants. They inoculated mice with lung cancer cells. One third received nothing (the control group), one third received the chemotherapy drug adriamycin, and one third received the main graviola acetogenin, annonacin (at a dosage of 10 mg/kg). At the end of two weeks, five of the six in the untreated control group were still alive and lung tumor sizes were then measured. The adriamycin group showed a 54.6% reduction of tumor mass over the control group—but 50% of the animals had died from toxicity (three of six). The mice receiving annonacin were all still alive, and the tumors were inhibited by 57.9%—slightly better than adriamycin—and without toxicity. This led the researchers to summarize; “This suggested that annonacin was less toxic in mice. On considering the antitumor activity and toxicity, annonacin might be used as a lead to develop a potential anticancer agent.”
Current Practical Uses
Cancer research is ongoing on these important Annona plants and plant chemicals, as several pharmaceutical companies and universities continue to research, test, patent, and attempt to synthesize these chemicals into new chemotherapeutic drugs. In fact, graviola seems to be following the same path as another well known cancer drug – Taxol. From the time researchers first discovered an antitumorous effect in the bark of the pacific yew tree and a novel chemical called taxol was discovered in its bark - it took thirty years of research by numerous pharmaceutical companies, universities, and government agencies before the first FDA-approved Taxol drug was sold to a cancer patient (which was based on the natural taxol chemical they found in the tree bark). With graviola, it has taken researchers almost 10 years to successfully synthesize (chemically reproduce) the main antitumorous chemical, annonacin. These acetogenin chemicals have a unique waxy center and other unique molecular energy properties which thwarted earlier attempts, and at least one major pharmaceutical company gave up in the process (despite knowing how active the natural chemical was against tumors). Now that scientists have the ability to recreate this chemical and several other active acetogenins in the laboratory, the next step is to change the chemical just enough (without losing any of the antitumorous actions in the process) to become a novel chemical which can be patented and turned into a new patented cancer drug. (Naturally-occurring plant chemicals cannot be patented.) Thus far, scientists seem to be thwarted again—every time they change the chemical enough to be patentable, they lose much of the antitumorous actions. Like the development of taxol, it may well take government agenies like the National Cancer Institute and the National Institute of Health to step forward and launch full-scale human cancer research on the synthesized unpatentable natural plant chemical (which will allow any pharmaceutical company to develop a cancer drug utilizing the research as happened with taxol) to be able to make this promising therapy available to cancer patients in a timely fashion.
In the meantime, many cancer patients and health practitioners are not waiting… they are adding the natural leaf and stem of graviola (with over 40 documented naturally-occurring acetogenins including annonacin) as a complementary therapy to their cancer protocols. After all, graviola has a long history of safe use as a herbal remedy for other conditions for many years, and research indicates that the antitumorous acetogenins are selectively toxic to just cancer cells and not healthy cells—and in miniscule amounts. While research confirms that these antitumorous acetogenins also occur in high amounts in the fruit seeds and roots of graviola, different alkaloid chemicals in the seeds and roots have shown some preliminary in vitro neurotoxic effects. Researchers have suggested that these alkaloids might be linked to atypical Parkinson’s disease in countries where the seeds are employed as a common herbal parasite remedy. Therefore, using the seeds and root of graviola is not recommended at this time.
The therapuetic dosage of graviola leaf, (which offers just as high of an amount of acetogenins as the root and almost as much as the seed) is reported to be 2-3 grams taken 3 or 4 times daily. Graviola products (capsules and tinctures) are becoming more widely available in the U.S. market, and now offered under several different manufacturer’s labels in health food stores. As one of graviola’s mechanisms of action is to deplete ATP energy to cancer cells, combining it with other supplements and natural products which increase or enhance cellular ATP may reduce the effect of graviola. The main supplement which increases ATP is a common antioxidant called Coenzyme Q10 and for this reason, it should be avoided when taking graviola.
Graviola is certainly a promising natural remedy and one that again emphasizes the importance of preserving our remaining rainforest ecosystems. Perhaps—if enough people believe that the possible cure for cancer truly is locked away in a rainforest plant—we will take the steps needed to protect our remaining rainforests from destruction. One researcher studying graviola summarized this idea eloquently: “At the time of preparation of this current review, over 350 Annonaceous acetogenins have been isolated from 37 species. Our preliminary efforts show that about 50%, of over 80 Annonaceous species screened, are significantly bioactive and are worthy of fractionation; thus, this class of compounds can be expected to continue to grow at an exponential rate in the future, provided that financial support for such research efforts can be found. With the demise of the world’s tropical rain forests, such work is compelling before the great chemical diversity, contained within these endangered species, is lost.”
GRAVIOLA PLANT SUMMARY
Main Actions (in order):
anticancerous, antitumorous, antimicrobial, antiparasitic, hypotensive (lowers blood pressure)
for cancer (all types)
as a broad-spectrum internal and external antimicrobial to treat bacterial and fungal infections
for internal parasites and worms
for high blood pressure
for depression, stress, and nervous disorders
Properties/Actions Documented by Research:
antibacterial, anticancerous, anticonvulsant, antidepressant, antifungal, antimalarial, antimutagenic (cellular protector), antiparasitic, antispasmodic, antitumorous, cardiodepressant, emetic (causes vomiting), hypotensive (lowers blood pressure), insecticidal, sedative, uterine stimulant, vasodilator
Other Properties/Actions Documented by Traditional Use:
antiviral, cardiotonic (tones, balances, strengthens the heart), decongestant, digestive stimulant, febrifuge (reduces fever), nervine (balances/calms nerves), pediculicide (kills lice), vermifuge (expels worms)
Cautions: It has cardiodepressant, vasodilator, and hypotensive (lowers blood pressure) actions. Large dosages can cause nausea and vomiting. Avoid combining with ATP-enhancers like CoQ10.
Traditional Preparation: The therapeutic dosage is reported to be 2 g three times daily in capsules or tablets. A standard infusion (one cup 3 times daily) or a 4:1 standard tincture (2–4 ml three times daily) can be substituted if desired. See Traditional Herbal Remedies Preparation Methods page if necessary for definitions.
Graviola has demonstrated uterine stimulant activity in an animal study (rats) and should therefore not be used during pregnancy.
Graviola has demonstrated hypotensive, vasodilator, and cardiodepressant activities in animal studies and is contraindicated for people with low blood pressure. People taking antihypertensive drugs should check with their doctors before taking graviola and monitor their blood pressure accordingly (as medications may need adjusting).
Graviola has demonstrated significant in vitro antimicrobial properties. Chronic, long-term use of this plant may lead to die-off of friendly bacteria in the digestive tract due to its antimicrobial properties. Supplementing the diet with probiotics and digestive enzymes is advisable if this plant is used for longer than 30 days.
Graviola has demonstrated emetic properties in one animal study with pigs. Large single dosages may cause nausea or vomiting. Reduce the usage accordingly if this occurs.
One study with rats given a stem-bark extract intragastrically (at 100 mg/kg) reported an increase in dopamine, norepinephrine, and monomine oxidase activity, as well as a inhibition of serotonin release in stress-induced rats.
Alcohol extracts of graviola leaf showed no toxicity or side effects in mice at 100 mg/kg; however, at a dosage of 300 mg/kg, a reduction in explorative behavior and mild abdominal constrictions was observed. If sedation or sleepiness occurs, reduce the amount used.
Drug Interactions: None have been reported; however, graviola may potentiate antihypertensive and cardiac depressant drugs. It may potentiate antidepressant drugs and interfere with MAO-inhibitor drugs. See contraindications above.
WORLDWIDE ETHNOMEDICAL USES
Brazil for abscesses, bronchitis, chest problems, cough, diabetes, diarrhea, dysentery, edema, fever, intestinal colic, intestinal parasites, liver problems, neuralgia, nervousness, pain, parasites, rheumatism, spasms, worms
Caribbean for chills, fever, flu, indigestion, nervousness, palpitations, rash, spasms, skin disease, and as a sedative
Curaçao for childbirth, gallbladder problems, nervousness, and as a sedative and tranquilizer
Haiti for digestive sluggishness, coughs, diarrhea, fever, flu, heart conditions, lactation aid, lice, nerves, parasites, pain, pellagra, sores, spasms, weakness, wounds, and as a sedative
Jamaica for asthma, fevers, heart conditions, hypertension, lactation aid, nervousness, parasites, spasms, water retention, weakness, worms, and as a sedative
Malaysia for boils, coughs, diarrhea, dermatosis, hypertension, rheumatism, and to reduce bleeding
Mexico for diarrhea, dysentery, fever, chest colds, ringworm, scurvy, and to reduce bleeding
Panama for diarrhea, dyspepsia, kidney, stomach ulcers, worms
Peru for diabetes, diarrhea, dysentery, fever, hypertension, indigestion, inflammation, lice, liver disorders, parasites, spasms, tumors, ulcers (internal), and as a sedative
Trinidad for blood cleansing, fainting, flu, high blood pressure, insomnia, lactation aid, palpitations, ringworms
U.S.A. for cancer, depression, fungal infections, hypertension, intestinal parasites, tumors
West Indies for asthma, childbirth, diarrhea, hypertension, lactation aid, parasites, worms
Elsewhere for arthritis, asthma, bile insufficiency, childbirth, cancer, diarrhea, dysentery, fever, heart problems, kidney problems, lactation aid, lice, liver disorders, malaria, pain, ringworm, scurvy, stomach problems, and as a sedative
>>>>In his insightful book, Timeless Secrets of
Health & Rejuvenation, Andreas Moritz devotes
a full page (p.310) to the power of Graviola
to heal cancer. Here's some of what he has to
"Graviola is lethal to 12 different kinds of
malignant cancer cells, especially those that
cause lung, prostate, and Breast Cancer s. It
is also safe enough to protect healthy cells
instead of killing them, as chemotherapy does."
Andreas goes on to add that a billion-dollar
drug company tried -- and failed -- to
synthesize an artificial version of Graviola,
when their researchers found that Graviola was
10,000 TIMES more toxic to colon cancer cells
than a common chemo drug.
"Many terminal cases of cancer were reversed
through the use of Graviola, even in persons
85 years or older."
Andreas suggests that anyone taking graviola
should do intestinal cleansing every day
while taking the herb. Why? Because the
Graviola breaks up tumors, and the still-lethal bits and pieces can become stuck in
the colon, small intestine, or kidneys.
Enenmas, colonics, and kidney cleanses will
clean out the toxic debris. Be prepared,
however, to undergo a healing crisis, with
all its discomforts.
>>>>How many people died in vain while this billion-dollar
drug maker concealed the secret of the miraculous Graviola tree?
Deep within the Amazon Rainforest grows a tree that could literally revolutionize what you, your doctor, and the rest of the world thinks about cancer treatment and chances of survival. The future has never looked more promising.
Research shows that with extracts from this miraculous tree it now may be possible to:
Attack cancer safely and effectively with an all-natural therapy that does not cause extreme nausea, weight loss and hair loss; protect your immune system and avoid deadly infections; feel stronger and healthier throughout the course of the treatment; boost your energy and improve your outlook on life.
The source of this information is just as stunning: It comes from one of America's largest drug manufacturers, the fruit of over 20 laboratory tests conducted since the 1970's! What those tests revealed was nothing short of mind numbing... Extracts from the tree were shown to:
Effectively target and kill malignant cells in 12 types of cancer, including colon, breast, prostate, lung and pancreatic cancer.
The tree compounds proved to be up to 10,000 times stronger in slowing the growth of cancer cells than Adriamycin, a commonly used chemotherapeutic drug!
What's more, unlike chemotherapy, the compound extracted from the Graviola tree selectively hunts down and kills only cancer cells. It does not harm healthy cells!
The amazing anti-cancer properties of the Graviola tree have been extensively researched--so why haven't you heard anything about it? If Graviola extract is as half as promising as it appears to be--why doesn't every single oncologist at every major hospital insist on using it on all his or her patients?
Graviola--the plant that worked too well.
One of America's biggest billion-dollar drug makers began a search for a cancer cure and their research centered on Graviola, a legendary healing tree from the Amazon Rainforest.
Various parts of the Graviola tree--including the bark, leaves, roots, fruit and fruit-seeds--have been used for centuries by medicine men and native Indians in South America to treat heart disease, asthma, liver problems and arthritis. Going on very little documented scientific evidence, the company poured money and resources into testing the tree's anti-cancerous properties--and were shocked by the results. Graviola proved itself to be a cancer-killing dynamo.
The company had one huge problem with the Graviola tree--it's completely natural, and so, under federal law, not patentable. There's no way to make serious profits from it.
It turns out the drug company invested nearly seven years trying to synthesize two of the Graviola tree's most powerful anti-cancer ingredients. If they could isolate and produce man-made clones of what makes the Graviola so potent, they'd be able to patent it and make their money back. Alas, they hit a brick wall. The original simply could not be replicated. There was no way the company could protect its profits--or even make back the millions it poured into research.
As the dream of huge profits evaporated, their testing on Graviola came to a screeching halt. Even worse, the company shelved the entire project and chose not to publish the findings of its research!
Luckily, however, there was one scientist from the Graviola research team whose conscience wouldn't let him see such atrocity committed. Risking his career, he contacted a company that's dedicated to harvesting medical plants from the Amazon Rainforest and blew the whistle.
When researchers at the Health Sciences Institute were alerted to the news of Graviola, they began tracking the research done on the cancer-killing tree. Evidence of the astounding effectiveness of Graviola--and its shocking cover-up--came in fast and furious...
The National Cancer Institute performed the first scientific research in 1976. The results showed that Graviola's "leaves and stems were found effective in attacking and destroying malignant cells." Inexplicably, the results were published in an internal report and never released to the public.
Since 1976, Graviola has proven to be an immensely potent cancer killer in 20 independent laboratory tests--yet no double-blind clinical trials, the typical benchmark mainstream doctors and journals use to judge a treatment's value--were ever initiated...
A study published in the Journal of Natural Products, following a recent study conducted at Catholic University of South Korea stated that one chemical in Graviola was found to selectively kill colon cancer cells at "10,000 times the potency of (the commonly used chemotherapy drug) Adriamycin..."
The most significant part of the Catholic University of South Korea report is that Graviola was shown to selectively target the cancer cells leaving healthy cells untouched. Unlike chemotherapy, which indiscriminately targets all actively reproducing cells (such as stomach and hair cells), causing the often devastating side effects of nausea and hair loss in cancer patients.
A study at Purdue University recently found that leaves from the Graviola tree killed cancer cells among six human cell lines and were especially effective against prostate, pancreatic and lung cancers.
Autoimmune disease is the immune system's "over reaction" to a toxin. Remove the toxin and you "herx". Then you feel better.
I have auto-immune issues -- I took SAMENTO (TOA-free Cat's Claw) and got really sick (major herx reaction). However -- once I started Lugol's and dosed therapeutically for MONTHS I went back on the SAMENTO -- at the same time as the Lugol's and didn't herx at all.
So -- whatever I had was made better by the Lugol's and allowed the SAMENTO to do its job.
Still dealing with feeling like crap some days -- but I am working a five day sometimes ten hour days work week, have a full schedule at church and at home, so -- it's all good.
I also recommend FAR INFRA RED sauna treatments. You can get as elaborate or as simple as you like - but you have to move the fluid -- you have to sweat, poop, pee, and get all of that *&^% out of you.
Do you have Lyme co-infections for why you had the reaction to the Samento? Didn't you also have a reaction to it Miss H?
Ugh...toxins. For sure it all goes together and is a whole bigger picture. I knew a year ago that Radiation was something that had come up high on the Biofeedback computer testing the Alt Dr had done, but at that time, the load of parasites and trying to get the liver working were the biggest focus- and it was kind of "forgotten"...
Not now. I just did the test again yesterday, for all the organs--and like big Neon signs blinking, Radiation is the #1 thing that kept showing up that I need to address. He "imprinted" homeopathics for me for getting it out of my organs over the next month..but yes, the other thing that I have been having to hit is the Lyme co-infections, from a tick bite 40 years ago that I was so sick from.
Newport told me to have him specifically check for a couple of other co-infections that is usually found too, and sure enough, I had the Alt Dr specifically check for Bartonella yesterday and it showed up strong. I'll be doing another Lyme series that has the Babesia, Borrelia, and Ehrlichia in it again, and another series with the Bartonella.
But..the good thing was the Rocky Mountain Spotted Fever didn't show up for the first time yesterday, after doing 2 series for it.
I also just started with the 9 mg of Boron last week, which I should have been doing all along (for radiation), and have upped the Lugol's without having problems like I expected (I was chicken, I admit it).
I "spring a leak" (tears) with a soft spot, and alot of respect in my heart for anything to do with military that have served, and are serving...and for military families too. Just reading posts of yours and Trapper's in honor of Veteran's Day had my shirt soaked. When my daughter was in AF, she asked me if I would make a couple of crocheted blankets for a couple of friends of her's for Christmas- brothers that were serving together. She handed both blankets to the one brother, and told him her mom had made them for them. She said he got quiet, and choked up...and told her "you'll never know how much this means to us...our mom died last year". I know how much it means to them to know they are being thought of, and are not forgotten. I don't know if I can give the site here, but I send magazines to the deployed that I've "adopted" from a website where they can make requests (usually small, "comfort" items that we tend to take for granted) I like reading through the site to see the pictures they've posted.
BTW...to get back on topic now :) Thanks for the info on taking the dosages of IP6!
i read all that and decided to give the ip 6 another try for more than just tooth powder
this time i had my glasses on and noticed that you are supposed take it on an empty stomach, so i did right this time
about thirty minutes later i could feel a creepy crawly sensation in my head
i haven't felt anything similar since last march, thought i got rid of the brain squirm with boswellia serrata, this movement was more subtle and covered a larger area
was it a coincidence? not
last evening i took another dose on an empty stomach and it happened again
the stuff is cleaning something out of my brain, near my right temple, where i have a suspicious mole