Biofilm is thought by some LLMD's to be one of those "snags" to healing Lyme disease. As mentioned in a previous post, sometimes bacteria and other microbes cloak themselves in biofilm, a polysaccharide matrix comprised of minerals, metals and other elements, to protect themselves from anti-microbial treatments, which prevents antibiotics and other Lyme strategies from being fully effective.
When biofilm exists in the gut, it also disturbs digestion and prevents normal flora (like acidophilus) from thriving. If you have persistent dysbiosis, mysterious gut pain, or a borrelia infection that simply isn't responding to treatments, consider the possibility that biofilm may be impeding your progress.
Unfortunately, medicine is still in its infancy when it comes to understanding biofilm and its role in Lyme disease. It is even less equipped to offer effective treatments that will break it down so that microbes can be accessed and eliminated.
Combining enzymes with heavy metal chelators (since the biofilm is comprised in part, of metals), and taking these on an empty stomach, is thought to be one potentially effective strategy for "punching holes" in the biofilm and thereby breaking down the bugs' protective polysaccharide blankies. Once this is done, then the Lyme sufferer can take anti-microbials to attack bacteria, yeast and other bugs. Subsequently, toxin binders can be ingested to clean up the mess left behind by the dead critters.
Tentatively, some of the enzymatic products that are currently being used for the hole-punching process include: SPS 30 (www.theramedix.net) and Mucostop by Enzymedica (www.enzymedica.com). Other enzymes that are being experimented with for Lyme sufferers with gut biofilm include: Lumbrokinase, Rechts-Regulat and serrapeptase. These latter enzymes, incidentally, are also widely used for hypercoagulation in Lyme. (So you might be able to kill two birds with one stone here; that is, break down biofilm while treating hypercoagulation).
Gut biofilm toxin binders, according to Dr. A. Derksen, a Lyme-literate N.D., include: fiber, clays, zeolites, chlorella, modifilan, apple pectin, butyrate, Bentonite and activated charcoal.
A heavy metal protocol may comprise any myriad of options, which I have discussed (and will continue to discuss) in other blog posts.
In the meantime, how do you know if you have gut biofilm? Well, isn't that always the question in Lyme disease? We never seem to know what's wrong with us, do we?
My humble suggestion (which should never to be taken as medical advice! I'm just a researcher, not a medical expert), if you have any of the above-named conditions, and are actively chelating metals and treating hypercoagulation, would be to take your chelator, if possible, at the same time that you take your enzymes for hypercoagulation. After that, take your bug-killers, and over time, see if that seems to be more effective than the schedule that you used to follow for taking all of the above.
If you aren't chelating metals or taking enzymes already, deciding whether to treat for biofilm may be a tougher decision. In any case, I would advise seeking out a biofilm-literate Lyme doctor (which are bound to be even more scarce than LLMD's).
I don't know how seriously we should take the idea of biofilm and its role in Lyme disease. Perhaps more than we have been, but not to the exclusion of other roadblocks to healing, as there are often many. This is just another one you may want to consider.
>>Tentatively, some of the enzymatic products that are currently being used for the hole-punching process include: SPS 30 (www.theramedix.net) and Mucostop by Enzymedica (www.enzymedica.com)<<
Did some digging and discovered that SPS 30 by Theramedix and Mucostop by Enzymedica have two proteolytic enzymes in common, unique to these products exclusively. Serrapeptase and what they call "Mucolase". But Mucolase (more digging) is not the specific "enzyme" name, more likely a proprietary thing - it's actually known in the enzyme universe as Seaprose.
"The flagship ingredients in the formula are nattokinase and another powerful enzyme called Seaprose-S. Until Barron brought us the news of his new formula, we weren't familiar with Seaprose-S. Research on it in this country is still in relatively early stages, but it has been used for over 30 years in Japan. In fact, Seaprose-S appears to be a natural antibiotic that can kill the bacteria responsible for many of the most common - and dangerous - diseases in the world."
Interesting that Nattokinase is mentioned also. It's known to have similar properties to Serrapeptase.
I love the following site for info on enzymes - page below contains loads of research info on Seaprose:
>>Weekly sessions of B.fragilis (DNA) are now leaving me Hg toxic and expelling rude stuff...
How do Bf freqs "cause" (improper word choice/understanding on my part??) mercury toxicity? (A serious question.) Are you suggesting it's creating, or extracting without a binder? Or is it that some binder you're using is grabbing it afterward and causing the "expulsion"?
sometimes bacteria and other microbes cloak themselves in biofilm, a polysaccharide matrix comprised of minerals, [HEAVY] metals and other elements, to protect themselves from anti-microbial treatments,
I am currently trying to do some parapunching myself.................
I am now taking Muccostop with xylanase , invertase, hemicellulase, mucolase, alpha galactosidase etc between meals on an empty stomach.........
also taking two pH basics from same company at bedtime (enzymedica) and one in the morning............ I also take two mastic gum before breakfast............... This enzymedica stuff is way too expensive and would not have been able to try if it wasn't given to me. I will be trying virastop from same company when I am done with muccostop. Virastop looks a little more reliable since it really goes after protein invaders. Serratiopepsidase and NSK-SD in there.
I also take jarrow formulas cold extracted porcine pancreatic enzymes with meals and Parazyme after meals - calcium butyrate, cellulase, probiotic blend, pepsin, quercetin, NAG, Gamma oryzanol, pepsin, bromelein.
Candex was also a good product for the amount of enzymes but too expensive also.
I have definitely seen some improvement like not being able to recognize aqnything in my stool anymore...........
nothing it ALL comes out digested. Still got the white tongue/sore throat thing though....................
Any questions on the enzymes I am taking let me know............
newport, cora...do you think enyzmes that contain the usual protease, lipase, amylase will work on biofilm? i use ultragest enzymes (has 1,320,000 !! usp protease per tablet). it'd be a nice bonus if it broke down biofilm too.